Results 61 to 70 of about 1,322,417 (342)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Mean-Square Strong Stability and Stabilization of Discrete-Time Markov Jump Systems with Multiplicative Noises

open access: yesMathematics, 2022
In this paper, the mean-square strong stability and stabilization of discrete-time Markov jump systems are studied. Firstly, the definition of mean-square strong stability is given, and the necessary and sufficient conditions for mean-square strong ...
Zhiguo Yan, Fangxu Su
doaj   +1 more source

On Channel Resolvability in Presence of Feedback

open access: yes, 2016
We study the problem of generating an approximately i.i.d. string at the output of a discrete memoryless channel using a limited amount of randomness at its input in presence of causal noiseless feedback. Feedback does not decrease the channel resolution,
Parizi, Mani Bastani, Telatar, Emre
core   +1 more source

Optimal Control of Two-Player Systems with Output Feedback [PDF]

open access: yes, 2015
In this article, we consider a fundamental decentralized optimal control problem, which we call the two-player problem. Two subsystems are interconnected in a nested information pattern, and output feedback controllers must be designed for each subsystem.
Lall, Sanjay, Lessard, Laurent
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Research on output feedback control [PDF]

open access: yes
A summary is presented of the main results obtained during the course of research on output feedback control. The term output feedback is used to denote a controller design approach which does not rely on an observer to estimate the states of the system.
Calise, Anthony J.
core   +4 more sources

Singular Perturbation Theory in Output Feedback Control of Pure-Feedback Systems

open access: yesIranian Journal of Electrical and Electronic Engineering, 2016
This paper studies output feedback control of pure-feedback systems with immeasurable states and completely non-affine property. Since availability of all the states is usually impossible in the actual process, we assume that just the system output is ...
M. Asadi, H. Toossian Shandiz
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Decentralized Adaptive Tracking of Interconnected Nonlinear Systems by Corrupted Output Feedback

open access: yesMathematics, 2020
A decentralized adaptive resilient output-feedback stabilization strategy is presented for a class of uncertain interconnected nonlinear systems with unknown time-varying measurement sensitivities.
Dong Min Jeong, Sung Jin Yoo
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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