Results 101 to 110 of about 128,146 (288)

Expression of VPAC1 in a murine model of allergic asthma [PDF]

open access: yes, 2013
Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways.
Braun, Armin   +4 more
core  

Performance evaluation of optical attocells configuration in an indoor visible light communication [PDF]

open access: yes, 2019
Visible light communication VLC is deemed as futuristic technology applied for both illumination and data communication due to the low-cost energy consumption, long life expectancy, huge bandwidth, and high security compared to radio frequency RF ...
Abdullah, Mohammad Faiz Liew   +1 more
core   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

open access: yesAdvanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim   +10 more
wiley   +1 more source

Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias

open access: yesAdvanced Science, EarlyView.
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei   +32 more
wiley   +1 more source

Proliferasi Limfosit Mencit BALB/c setelah Pemberian Ubi Jalar Ungu (Ipomoea batatas L.) Diinduksi Ovalbumin

open access: yesMutiara Medika, 2015
Kandungan flavonoid dalam ubi jalar ungu (Ipomoea batatas L.) berkhasiat  sebagai agen antialergi. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak etanol I. batatas L (EEIB).
Santin Meilandani   +1 more
doaj   +1 more source

Nuclear receptors in vascular biology [PDF]

open access: yes, 2015
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics.
A Chawla   +56 more
core   +3 more sources

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun   +8 more
wiley   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

open access: yesAdvanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan   +10 more
wiley   +1 more source

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