Results 181 to 190 of about 128,146 (288)

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan   +9 more
wiley   +1 more source

Prospective of indigenous African wild food plants in alleviation of the severe iron deficiency anaemia in Sub‐Saharan Africa

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Iron deficiency anaemia remains a major public health challenge in Sub‐Saharan Africa, where population growth, displacement and limited resources heighten nutritional insecurity. We compiled a list of indigenous African underutilized wild food plants and examined their potential for addressing micronutrient deficiencies.
Eltayb Abdellatef   +2 more
wiley   +1 more source

Rosmarinic Acid as A Flavonoids Ameliorated Cytokines and Oxidative Stress Biomarkers in the Lung Lavage Fluid of Rats. [PDF]

open access: yesFood Sci Nutr
Levels of IL‐4, IFN‐γ and NO2 in broncho alveolar lavage fluid (BALF). ABSTRACT Allergic asthma is a chronic respiratory condition characterized by pronounced inflammation, oxidative stress, and reversible airway obstruction. The objective of this study was to assess the effects of rosmarinic acid (RosA) on the mitigation of inflammation and oxidative ...
Abbasnia V, Foadoddini M, Khazdair MR.
europepmc   +2 more sources

Cigarette Smoke Increases CD8α+ Dendritic Cells in an Ovalbumin-Induced Airway Inflammation [PDF]

open access: gold, 2017
Thayse R. Brüggemann   +5 more
openalex   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

open access: yesAllergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng   +20 more
wiley   +1 more source

Serine/threonine kinase 33 mediates thrombin-induced interleukin-8 release from human lung epithelial cells in severe asthma. [PDF]

open access: yesRespir Res
Cheng WH   +9 more
europepmc   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

open access: yesAllergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek   +7 more
wiley   +1 more source

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