Results 21 to 30 of about 72,014 (249)

The Effect of Heparin on Antigen-Induced Mucus Hypersecretion in the Nasal Epithelium of Sensitized Rats

open access: yesAllergology International, 2013
Background: Heparin is a potential anti-inflammatory drug for allergic airway inflammation. To elucidate the effects of heparin on allergic inflammation, we examined the in vivo effects of heparin on antigen-induced mucus hypersecretion and infiltration ...
Takao Ogawa   +2 more
doaj   +1 more source

Cationic and Biocompatible Polymer/Lipid Nanoparticles as Immunoadjuvants

open access: yesPharmaceutics, 2021
Nanostructures have been of paramount importance for developing immunoadjuvants. They must be cationic and non-cytotoxic, easily assembling with usually oppositely charged antigens such as proteins, haptens or nucleic acids for use in vaccines.
Yunys Pérez-Betancourt   +5 more
doaj   +1 more source

Role of Ovalbumin/β-Cyclodextrin in Improving Structural and Gelling Properties of Culter alburnus Myofibrillar Proteins during Frozen Storage

open access: yesApplied Sciences, 2021
This study aimed to analyze the cryoprotective effect of a ovalbumin (OVA) and β-cyclodextrin (βCD) mixture (3:1, OVA/βCD) on the structure, rheology and gelling properties of myofibrillar proteins (MPs) during 90 days of frozen storage. A mixture of OVA/
Meiwen Lv   +10 more
doaj   +1 more source

The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice

open access: yesVaccines, 2021
Our aim was to determine whether polyphosphazene (PCEP), Curdlan (β-glucan, a dectin-1 agonist), and Leptin could act as adjuvants to promote a Th17-type adaptive immune response in mice.
Alyssa Chaffey   +4 more
doaj   +1 more source

Fluorescent Probes with Förster Resonance Energy Transfer Function for Monitoring the Gelation and Formation of Nanoparticles Based on Chitosan Copolymers

open access: yesJournal of Functional Biomaterials, 2023
Nanogel-forming polymers such as chitosan and alginic acid have a number of practical applications in the fields of drug delivery, food technology and agrotechnology as biocompatible, biodegradable polymers.
Igor D. Zlotnikov   +2 more
doaj   +1 more source

Conformational Changes Involved in the Switch from Ovalbumin to S-Ovalbumin

open access: yesZeitschrift für Naturforschung C, 1996
Abstract For the first time a comparative study on conformational differences between native oval­ buminand its heat-stable form, called S-ovalbumin. using small angle x-ray scattering, is reported. To detect a different pathway in the folding mechanism of the two proteins, scatter­ing measurements have been performed on ovalbumin and S ...
Castellano AC   +5 more
openaire   +4 more sources

Development of a vaccine adjuvant based on squalene and study of its adjuvant properties

open access: yesМедицинская иммунология, 2023
The use of modern subunit vaccines involves adjuvant introduction into their composition. Currently, the search for new and improvement of existing adjuvant systems is actively underway.
E. A. Volosnikova   +6 more
doaj   +1 more source

Therapeutic effects of a combination of Chinese quince and Saururus chinensis extract on allergic airway inflammation in an ovalbumin-induced asthma mouse model

open access: yesFrontiers in Nutrition
BackgroundAllergic asthma involves chronic inflammation, airway remodeling, and hyperresponsiveness. Inhaled corticosteroids combined with long-acting β2 agonists are effective; however, some patients experience side effects, highlighting the need for ...
Hye Jin Lee   +9 more
doaj   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

open access: yesHepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen   +4 more
wiley   +1 more source

Analysis of the Interaction Mechanism and Functional Characterisation of Quercetin and Ovalbumin

open access: yesShipin gongye ke-ji
To investigate the binding mechanism of the interaction between the natural bacteriostatic flavonoid polyphenol quercetin (Q) and ovalbumin (OVA) as well as the changes in the structure and bacteriostatic activity.
Hui CHEN   +6 more
doaj   +1 more source

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