Results 31 to 40 of about 119,117 (282)

The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice

Vaccines, 2021
Our aim was to determine whether polyphosphazene (PCEP), Curdlan (β-glucan, a dectin-1 agonist), and Leptin could act as adjuvants to promote a Th17-type adaptive immune response in mice.
Alyssa Chaffey, Glenn Hamonic, Dylan Chand, George K. Mutwiri, Heather L. Wilson   +4 more
doaj   +1 more source

Fluorescent Probes with Förster Resonance Energy Transfer Function for Monitoring the Gelation and Formation of Nanoparticles Based on Chitosan Copolymers

Journal of Functional Biomaterials, 2023
Nanogel-forming polymers such as chitosan and alginic acid have a number of practical applications in the fields of drug delivery, food technology and agrotechnology as biocompatible, biodegradable polymers.
Igor D. Zlotnikov, Ivan V. Savchenko, Elena V. Kudryashova   +2 more
doaj   +1 more source

Lung inflammation by fungus, Bjerkandera adusta isolated from Asian sand dust (ASD) aerosol and enhancement of ovalbumin-induced lung eosinophilia by ASD and the fungus in mice. [PDF]

, 2014
BackgroundBjerkandera adusta (B. adusta) is one of the most important etiological fungi associated with chronic cough. However, precise details of the inflammatory response to exposure are not well understood yet. B.
Arashidani, Keiichi, He, Miao, Ichinose, Takamichi, Kobayashi, Fumihisa, Liu, Boying, Maki, Teruya, Nishikawa, Masataka, Shibamoto, Takayuki, Sun, Guifan, Takano, Hirohisa, Yoshida, Seiichi, Yoshida, Yasuhiro   +11 more
core   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

Hepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen, Yu‐Chia Su, Yee‐Ern Or, Chin‐Fu Cheng, John T. Kung   +4 more
wiley   +1 more source

Development of a vaccine adjuvant based on squalene and study of its adjuvant properties

Медицинская иммунология, 2023
The use of modern subunit vaccines involves adjuvant introduction into their composition. Currently, the search for new and improvement of existing adjuvant systems is actively underway.
E. A. Volosnikova, D. N. Shcherbakov, V. V. Ermolaev, N. V. Volkova, O. N. Kaplina, M. B. Borgoyakova, E. D. Danilenko   +6 more
doaj   +1 more source

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid, Baker, Lauren L., Cambrook, Helen, Finigan, Alison J., Grassia, Gianluca, Hansson, Göran K., Harrison, James E., Hugues, Stéphanie, Ludewig, Burkhard, Maffia, Pasquale, Mallat, Ziad, Masters, Leanne M., Murphy, Deirdre, Reith, Walter, Reizis, Boris, Sabir, Suleman, Sage, Andrew P.   +16 more
core   +2 more sources

Therapeutic effects of a combination of Chinese quince and Saururus chinensis extract on allergic airway inflammation in an ovalbumin-induced asthma mouse model

Frontiers in Nutrition
BackgroundAllergic asthma involves chronic inflammation, airway remodeling, and hyperresponsiveness. Inhaled corticosteroids combined with long-acting β2 agonists are effective; however, some patients experience side effects, highlighting the need for ...
Hye Jin Lee, Ki Cheon Kim, Woo Jin Lee, Hyo Jung Nam, Su Jin Ryu, Seon Hyeok Kim, Won Jun Kim, Jae Won Yoon, Tae-Hee Lee, Pan-Young Jeong   +9 more
doaj   +1 more source

Analysis of the Interaction Mechanism and Functional Characterisation of Quercetin and Ovalbumin

Shipin gongye ke-ji
To investigate the binding mechanism of the interaction between the natural bacteriostatic flavonoid polyphenol quercetin (Q) and ovalbumin (OVA) as well as the changes in the structure and bacteriostatic activity.
Hui CHEN, Lili LIU, Weiwei CHENG, Yue DING, Baocheng XU, Feng XIAO, Jialiang HE   +6 more
doaj   +1 more source

miR-30a-3p participates in the development of asthma by targeting CCR3

Open Medicine, 2020
This study aimed to investigate the role and relevant mechanism of miR-30a-3p action in asthma. The results of this study revealed that the expression levels of miR-30a-3p were significantly decreased in the peripheral blood of asthmatic patients.
Li Xiaobo, Wang Binliang, Huang Mao, Wang Xiaomi   +3 more
doaj   +1 more source

Development and in vitro evaluation of recombinant chicken promoters to efficiently drive transgene expression in chicken oviduct cells

Poultry Science, 2021
: Virus injection into EGK-X embryos is a well-defined approach in avian transgenesis. This system uses a chicken ovalbumin gene promoter to induce transgene expression in the chicken oviduct.
Hyeon Yang, Bo Ram Lee, Hwi-Cheul Lee, Hoonsung Choi, Sun Keun Jung, Ji-Youn Kim, Jingu No, Sureshkumar Shanmugam, Yong Jin Jo, Keon Bong Oh, Kyung Woon Kim, Sung June Byun   +11 more
doaj   +1 more source