Results 171 to 180 of about 755,388 (347)
Simulation Study of Low-Dose Sparse-Sampling CT with Deep Learning-Based Reconstruction: Usefulness for Evaluation of Ovarian Cancer Metastasis [PDF]
, 2020 Yasuyo Urase +9 more
openalex +1 more source
Advanced Science, EarlyView.The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song +11 more
wiley +1 more source
Advanced Science, EarlyView.This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen +17 more
wiley +1 more source
Effect of first line cancer treatment on the ovarian reserve and follicular density in girls under the age of 18 years [PDF]
, 2016 Meryam El Issaoui +7 more
openalex +1 more source
Multiscale Construction, Evaluation, and Application of Organoids
Advanced Science, EarlyView.Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma +5 more
wiley +1 more source
TOP2A as marker of response to pegylated lyposomal doxorubicin (PLD) in epithelial ovarian cancers [PDF]
, 2019 Eleonora Ghisoni +13 more
openalex +1 more source
Advanced Science, EarlyView.Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 ...
Xiangui Meng +6 more
wiley +1 more source
Ovarian carcinosarcoma is highly aggressive compared to other ovarian cancer histotypes
Frontiers in OncologyBackgroundOvarian carcinosarcoma (OCS) is an unusual ovarian cancer type characterized by distinct carcinomatous and sarcomatous components. OCS has been excluded from many of the pan-histotype studies of ovarian carcinoma, limiting our understanding of ...
Iona McFarlane +6 more
doaj +1 more source
Chemotherapy-induced apoptosis, autophagy and cell cycle arrest are key drivers of synergy in chemo-immunotherapy of epithelial ovarian cancer [PDF]
, 2018 John Wahba +9 more
openalex +1 more source