MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer. [PDF]
, 2015 Development of multidrug resistance (MDR) is an almost universal phenomenon in patients with ovarian cancer, and this severely limits the ultimate success of chemotherapy in the clinic.
Amiji, Mansoor M +6 more
core +1 more source
Reducing Histopathology Slide Magnification Improves the Accuracy and Speed of Ovarian Cancer Subtyping [PDF]
arXiv, 2023 Artificial intelligence has found increasing use for ovarian cancer morphological subtyping from histopathology slides, but the optimal magnification for computational interpretation is unclear. Higher magnifications offer abundant cytological information, whereas lower magnifications give a broader histoarchitectural overview.
arxiv
Can 9q34.2 rs633862 polymorphism predict survival in epithelial ovarian cancer? [PDF]
PeerJ, 2017 Objective Our previous genome-wide association study (GWAS) identified that the ABO rs633862 variant in chromosome 9q34.2 was associated with the risk of epithelial ovarian cancer (EOC) in Chinese Han women.
Rong Jiang +5 more
doaj +2 more sources
The accurate staging of ovarian cancer using 3T magnetic resonance imaging - a realistic option [PDF]
, 2008 Objectives: The aim of the study was to determine whether staging primary ovarian cancer using 3.0 Tesla (3T) magnetic resonance imaging (MRI) is comparable to surgical staging of the disease.
Booth, SJ +3 more
core +1 more source
Predicting Ovarian Cancer Treatment Response in Histopathology using Hierarchical Vision Transformers and Multiple Instance Learning [PDF]
arXiv, 2023 For many patients, current ovarian cancer treatments offer limited clinical benefit. For some therapies, it is not possible to predict patients' responses, potentially exposing them to the adverse effects of treatment without any therapeutic benefit.
arxiv
Epithelial ovarian cancer: Evolution of management in the era of precision medicine
Ca, 2019 Ovarian cancer is the second most common cause of gynecologic cancer death in women around the world. The outcomes are complicated, because the disease is often diagnosed late and composed of several subtypes with distinct biological and molecular ...
S. Lheureux, Marsela Braunstein, A. Oza
semanticscholar +1 more source
Nature Communications, 2021 Several strategies have been attempted to target immune suppressive populations in the tumor microenvironment. Here the authors show that folate receptor β-targeted CAR-T cells eliminate immunosuppressive tumor associated macrophages, promoting ...
Alba Rodriguez-Garcia +10 more
doaj +1 more source
Family history of breast and ovarian cancer and triple negative subtype in hispanic/latina women. [PDF]
, 2014 Familial breast and ovarian cancer prevalence was assessed among 1150 women of Mexican descent enrolled in a case-only, binational breast cancer study. Logistic regression was conducted to compare odds of triple negative breast cancer (TNBC) to non-TNBC ...
Anderson, Kristin +13 more
core +2 more sources
Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer [PDF]
, 2016 The small GTPase Rab25 has been functionally linked to tumour progression and aggressiveness in ovarian cancer and promotes invasion in three-dimensional environments.
Chalmers, Anthony J. +3 more
core +1 more source
Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer
New England Journal of Medicine, 2018 BACKGROUND Treatment of newly diagnosed advanced‐stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to ...
W. V. van Driel +16 more
semanticscholar +1 more source