Results 81 to 90 of about 5,108,464 (344)

Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance

open access: yesCancer Research, 2020
Ovarian cancer metastatic progression can be restricted by targeting a critical regulator of lipid responses, FABP4. Adipocytes are critical for ovarian cancer cells to home to the omentum, but the metabolic changes initiated by this interaction are ...
A. Mukherjee   +8 more
semanticscholar   +1 more source

Advancing Research Alongside Patient Partners: Next-Generation Best Practices for Effective Collaboration in Health Research

open access: yesCurrent Oncology
Ovarian Cancer Canada’s Patient Partners in Research (PPiR) is a national volunteer-based program that trains and connects individuals with lived ovarian cancer (OC) experience to diverse research opportunities, to maximize the clinical relevance and ...
Ally C. Farrell   +4 more
doaj   +1 more source

Can 9q34.2 rs633862 polymorphism predict survival in epithelial ovarian cancer? [PDF]

open access: yesPeerJ, 2017
Objective Our previous genome-wide association study (GWAS) identified that the ABO rs633862 variant in chromosome 9q34.2 was associated with the risk of epithelial ovarian cancer (EOC) in Chinese Han women.
Rong Jiang   +5 more
doaj   +2 more sources

The Lived Experience of Ovarian Cancer [PDF]

open access: yes, 2011
It was estimated that in 2009,21,550 women would be diagnosed with ovarian cancer and 14.600 women would die from it. There are approximately 176,007 women living with ovarian cancer in the US.
Tyll, Jennifer
core   +1 more source

Risk of cancer after assisted reproduction: a review of the available evidences and guidance to fertility counselors [PDF]

open access: yes, 2018
Infertile women requiring ovarian stimulation and assisted reproduction techniques (ART) are faced with difficult issues. The fear that using hormones could increase their risk of cancer is the most significant.
Codacci-Pisanelli, G   +4 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Niraparib in ovarian cancer. results to date and clinical potential [PDF]

open access: yes, 2017
Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both ...
Benedetti Panici, Pierluigi   +5 more
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo

open access: yesScientific Reports
Epithelial ovarian cancer (EOC) metastasizes predominantly through multicellular aggregates known as spheroids, which disseminate within the peritoneal cavity and initiate secondary disease upon reattachment at distant sites.
Matthew J. Borrelli   +5 more
doaj   +1 more source

Transcriptomic Analyses of Ovarian Clear Cell Carcinoma Spheroids Reveal Distinct Proliferative Phenotypes and Therapeutic Vulnerabilities

open access: yesCells
Cancer cell spheroids autonomously form in the ascites fluid and are considered a conduit for epithelial ovarian cancer metastasis within the peritoneal cavity. Spheroids are homotypic, avascular 3D structures that acquire resistance to anoikis to remain
Bart Kolendowski   +4 more
doaj   +1 more source

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