Results 61 to 70 of about 86,402 (307)

Office Management of Ovarian Cysts [PDF]

open access: yesMayo Clinic Proceedings, 1997
Ovarian cysts are detected in female patients of all ages. The patient's age, the size of the cyst, and the ultrasound appearance are helpful in determining which ovarian cysts necessitate observation and which necessitate surgical excision. The cancer antigen 125 level alone does not help to distinguish between benign and malignant ovarian cysts.
Jeffrey L. Cornella, Javier F. Magrina
openaire   +2 more sources

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

open access: yesAdvanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui   +6 more
wiley   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

open access: yesAdvanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro   +10 more
wiley   +1 more source

Citrullination of AKT2 Catalyzed by PAD1 Facilitates the Maintenance of Stemness Characteristics of Ovarian Cancer Stem‐Like Cells in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue   +10 more
wiley   +1 more source

17β-Hydroxysteroid dehydrogenase type I and aromatase in ovarian cortical inclusion cysts

open access: yesEndocrine Connections
Previous evidence suggests a link between the ovarian surface epithelium and cortical inclusion cysts and the origin of epithelial ovarian cancer.
Enrique Pedernera   +6 more
doaj   +1 more source

Efficacy of Sclerotherapic Agents in the Treatment of Simple Ovarian Cysts Created by Experimental Rat Model

open access: yesİstanbul Medical Journal, 2020
Introduction:The purpose of this study is to investigate the effects of tetracycline (TC), clarithromycin (CM) and bleomycin (BLM) on the cyst diameter and ovarian tissues in the treatment of simple ovarian cysts.Methods:We employed Wistar albino female ...
Ünal Bakal   +6 more
doaj   +1 more source

Ovarian cysts [PDF]

open access: yesAmerican Journal of Obstetrics and Gynecology, 2021
openaire   +2 more sources

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

open access: yesAdvanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang   +6 more
wiley   +1 more source

Analysis of gonadocorticoids profile in canine patients diagnosed with ovarian cysts

open access: yesCluj Veterinary Journal
Veterinarians can obtain a more comprehensive understanding of the progression of ovarian cystic pathology in dogs by assessing hormonal levels. This study aimed to examine the gonadocorticoid profile of dogs diagnosed with ovarian cysts and compare ...
Zoltán-Miklós GÁL   +4 more
doaj   +1 more source

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu   +15 more
wiley   +1 more source

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