Application of Perinatal Derivatives in Ovarian Diseases [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Reproductive diseases could lead to infertility and have implications for overall health, most importantly due to psychological, medical and socio-economic consequences for individuals and society.
Anna Lange-Consiglio +7 more
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Reactive oxygen species and ovarian diseases: Antioxidant strategies [PDF]
Redox Biology, 2023 Reactive oxygen species (ROS) are mainly produced in mitochondria and are involved in various physiological activities of the ovary through signaling and are critical for regulating the ovarian cycle. Notably, the imbalance between ROS generation and the
Junzhi Liang +5 more
doaj +4 more sources
New insights on mitochondrial heteroplasmy observed in ovarian diseases [PDF]
Journal of Advanced ResearchBackground: The reportedly high mutation rate of mitochondrial DNA (mtDNA) may be attributed to the absence of histone protection and complete repair mechanisms. Mitochondrial heteroplasmy refers to the coexistence of wild-type and mutant mtDNA.
Yong Zhou +12 more
doaj +3 more sources
Early Warning for Ovarian Diseases Based on Plasma Non-esterified Fatty Acid and Calcium Concentrations in Dairy Cows [PDF]
Frontiers in Veterinary Science, 2021 Inactive ovaries (IO) and ovarian (follicular or luteal) cysts (FC or LC) are two common ovarian diseases leading to infertility in dairy cattle. Both disorders are associated with altered metabolites and hormones.
Yuxi Song +6 more
doaj +2 more sources
Assessing the knowledge, attitudes, and perceptions of ovarian cryopreservation technology among women with ovarian diseases [PDF]
Frontiers in Public HealthBackgroundCryopreservation techniques for laboratory oocytes provide women with increased reproductive options, especially for those facing fertility challenges due to ovarian diseases.AimThis study aimed to assess the knowledge, attitudes, and ...
Faten Mabrouk Nouh +14 more
doaj +2 more sources
A Narrative Review of Recent Insights on Nerve Growth Factor Signaling in Physiological and Pathological Ovarian Processes in Mammals [PDF]
BiomoleculesNerve Growth Factor (NGF), a member of the neurotrophin family, is currently regarded as a key regulator of ovarian physiology beyond its well-known neurotrophic functions.
Massimo Aloisi +2 more
doaj +2 more sources
The interaction between endoplasmic reticulum stress and ferroptosis in ovarian diseases [PDF]
Journal of Ovarian ResearchBackground Ovarian diseases including polycystic ovary syndrome (PCOS), premature ovarian insufficiency (POI) and ovarian cancer, critically impact women’s reproductive health. Growing evidence implicates endoplasmic reticulum (ER) stress and ferroptosis
Min Xing +5 more
doaj +2 more sources
Clinical Medicine Insights: Reproductive Health, 2012 Women with autoimmune diseases such as lupus, scleroderma, and vasculitis receiving cyclophosphamide for severe disease manifestations risk primary ovarian insufficiency (POI) due to gonadotoxicity of this therapy.
Wendy Marder +3 more
doaj +2 more sources
The mechanisms crosstalk and therapeutic opportunities between ferroptosis and ovary diseases
Frontiers in Endocrinology, 2023 Ferroptosis, a form of regulated cell death, was first defined in 2012. Ferroptosis mainly involves iron-driven lipid peroxidation damage of cells. This process is regulated by iron homeostasis, redox balance, lipid metabolism, glutathione metabolism ...
Ying Yao +4 more
doaj +1 more source
Ovarian cancer and BRCA mutation genetic testing: the Brazilian reality
Brazilian Journal of Oncology, 2021 Introduction: Ovarian cancer (OC) is one of the leading causes of women’s cancer deaths worldwide. Recent clinical trials with PARP inhibitors showed promising therapeutic opportunities for OC patients. The assessment of BRCA mutation is well established
Dalila Cunha de Oliveira +6 more
doaj +1 more source