Results 41 to 50 of about 352,140 (294)

Female germline stem cells: aging and anti-aging

Journal of Ovarian Research, 2022
The delay of ovarian aging and the fertility preservation of cancer patients are the eternal themes in the field of reproductive medicine. Acting as the pacemaker of female physiological aging, ovary is also considered as the principle player of cancer ...
Wenli Hong, Baofeng Wang, Yasha Zhu, Jun’e Wu, Li Qiu, Shuyi Ling, Ziqiong Zhou, Yuqing Dai, Zhisheng Zhong, Yuehui Zheng   +9 more
doaj   +1 more source

Laparoscopic surgeries for uterine fibroids and ovarian cysts reduce ovarian reserve via age- and surgical type-manner

Gynecological Endocrinology, 2022
Aim: Diminished ovarian reserve can be characterized by poor response to ovulation and low number of eggs. The risk factors include endometriosis, receiving cancer treatment, luteal phase deficiency and gynecologic surgery.
Xiaolong Shi, Shuo Chen, Yunling Yang, Limin Liu, Linlin Huang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hormonal therapy for ovarian dysfunctions in high-productive cows

BIO Web of Conferences, 2020
The analysis was made of culling data in the farm of the Udmurt Republic. As a result, it was found that the animals are eliminated due to gynecological and limb diseases. They make up 19–24 % and 18–31 % respectively.
Khamitova Liliya, Rudakov Roman, Knyazeva Mariya, Metlyakova Anastasiya   +3 more
doaj   +1 more source

Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey [PDF]

, 2020
Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their
Baccolini, V., Barnhoorn, F., D'Andrea, E., de Vito, C., Marco, M. D., Marzuillo, C., Paget, D. Z., Pitini, E., Rosso, A., Unim, B., Villari, P.   +10 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

TGF-β Signaling in the Pathophysiology of the Ovary: A Double-Edged Regulator

Biomolecules
The Transforming Growth Factor-β (TGF-β) superfamily comprises highly conserved cytokines that orchestrate key cellular functions, including proliferation, differentiation, and apoptosis. Within the ovary, TGF-β family members serve as pivotal regulators
Nicole Bertani, Alessandra Alteri, Luciana Cacciottola, Giorgia D’Addato, Gina La Sala, Biliana Lozanoska-Ochser, Micol Massimiani, Edoardo Parrella, Alessio Reggio, Eleonora Russo, Federica Campolo, Francesca Gioia Klinger   +11 more
doaj   +1 more source

Differential Diagnosis of Gynecologic Organ-Related Diseases in Women Presenting with Ascites

Taiwanese Journal of Obstetrics & Gynecology, 2008
Ascites is a pathologic accumulation of fluid within the peritoneal cavity, and usually develops as a result of liver disease, congestive heart failure or nephrotic syndrome. Ascites is also a common manifestation of some gynecologic diseases.
Ming-Huei Cheng, Ming-Shyen Yen, Kuan-Chong Chao, Bor-Ching Sheu, Peng-Hui Wang   +4 more
doaj   +1 more source

Estrogen Biosynthesis and Signal Transduction in Ovarian Disease

Frontiers in Endocrinology, 2022
Estrogen mainly binds to estrogen receptors (ERs) to regulate menstrual cycles and reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled estrogen receptor (GPER) mRNA could be detected in ovary, suggesting that they play an ...
Xue-Ling Xu, Zheng-Yuan Huang, Kun Yu, Jun Li, Xiang-Wei Fu, Shou-Long Deng   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source