Results 41 to 50 of about 215,664 (299)

Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis [PDF]

, 2009
Background: P53, egfr and her-2/neu are the most frequently studied molecular biological parameters in epithelial ovarian cancer, but their prognostic impact is still unequivocal.
de Jong, S., de Vries, E.G.E., de Bock, G.H.; id_orcid, Boezen, M., Post, W.J., van der Zee, A.G.J., de Vries, E.G.E.; id_orcid, Crijns, A.P.G., de Jong, S.; id_orcid, de Graeff, P., de Bock, G.H.   +10 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Hormonal therapy for ovarian dysfunctions in high-productive cows

BIO Web of Conferences, 2020
The analysis was made of culling data in the farm of the Udmurt Republic. As a result, it was found that the animals are eliminated due to gynecological and limb diseases. They make up 19–24 % and 18–31 % respectively.
Khamitova Liliya, Rudakov Roman, Knyazeva Mariya, Metlyakova Anastasiya   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Novel technologies in the treatment and monitoring of advanced and relapsed epithelial ovarian cancer [PDF]

, 2017
Epithelial ovarian cancer (EOC) is the fifth most common cause of cancer death in females in the UK. It has long been recognized to be a set of heterogeneous diseases, with high grade serous being the most common subtype.
Gowers, Sally, Cunnea, Paula, Fotopoulou, Christina, Drakakis, Emmanuel, Moore, James E, Boutelle, Martyn   +5 more
core   +1 more source

TGF-β Signaling in the Pathophysiology of the Ovary: A Double-Edged Regulator

Biomolecules
The Transforming Growth Factor-β (TGF-β) superfamily comprises highly conserved cytokines that orchestrate key cellular functions, including proliferation, differentiation, and apoptosis. Within the ovary, TGF-β family members serve as pivotal regulators
Nicole Bertani, Alessandra Alteri, Luciana Cacciottola, Giorgia D’Addato, Gina La Sala, Biliana Lozanoska-Ochser, Micol Massimiani, Edoardo Parrella, Alessio Reggio, Eleonora Russo, Federica Campolo, Francesca Gioia Klinger   +11 more
doaj   +1 more source

Laparoscopic surgeries for uterine fibroids and ovarian cysts reduce ovarian reserve via age- and surgical type-manner

Gynecological Endocrinology, 2022
Aim: Diminished ovarian reserve can be characterized by poor response to ovulation and low number of eggs. The risk factors include endometriosis, receiving cancer treatment, luteal phase deficiency and gynecologic surgery.
Xiaolong Shi, Shuo Chen, Yunling Yang, Limin Liu, Linlin Huang   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Ovarian Tumours and Ovarian Cancer

, 2020
Fertility preservation in women with ovarian tumours and ovarian cancer is a major challenge. Borderline ovarian tumours, malignant germ cell tumours and sex cord stromal tumours are tumour entities for which adequate surgical staging is recommended.
Wimberger, Pauline, Maren Goeckenjan, von Wolff, Michael, Michael von Wolff, Goeckenjan, Maren, Pauline Wimberger   +5 more
core   +1 more source

Metastatic ovarian carcinoma in white-tailed deer (Odocoileus virginianus) from a conservation center in Medellín-Colombia

Brazilian Journal of Veterinary Pathology
Wildlife animals in human care can develop pathological processes that rarely occur in their natural habitats, including neoplastic disorders. This report presents the post-mortem pathological findings of a white-tailed deer (Odocoileus virginianus) from
Santiago Duque-Arias, Alejandra Marín-Zapata, Jakob Restrepo-Rueda, Cristina Úsuga-Monroy, Horwald Alexander Bedoya Llano   +4 more
doaj   +1 more source