Results 61 to 70 of about 215,664 (299)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Severe Autoimmune Diseases

open access: yes, 2020
This section deals with ovarian protection in non-malignant, rheumatic or other autoimmune diseases. Since these diseases are disproportionately common in young women, knowledge of the negative effects of immunosuppressive agents on the ovarian reserve ...
Melanie Henes   +5 more
core   +1 more source

INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA

open access: yesSabiad, 2022
Objective: The most common cancers in women are breast, thyroid, colorectal, uterine corpus, lung and ovarian cancer. Ovarian cancer causes more than 150,000 deaths annually worldwide. The fact that this cancer manifests itself in the late stage and is a
Yasemin Gider   +9 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Socioeconomic Burden of Ovarian Cancer in 11 Countries

open access: yesJCO Global Oncology
PURPOSEOvarian cancer remains among the most aggressive tumors with the lowest survival probability. Projections are that ovarian cancer will claim more than 8 million lives between 2022 and 2050 without better prevention or control measures.METHODSWe ...
Brian Hutchinson   +9 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Ovarian Crohn's disease [PDF]

open access: yesJournal of Crohn's and Colitis, 2010
Dear Sir, Crohn's disease is a chronic inflammatory disorder that may involve any portion of the gastrointestinal tract. Predominant symptoms include abdominal pain, diarrhea and weight loss. The hallmark of Crohn's disease is bowel inflammation with fistula or stricture formation.
A. Ouakaa-Kchaou   +6 more
openaire   +1 more source

Fertility preservation: ovarian response to freeze oocytes is not affected by different malignant diseases-an analysis of 992 stimulations. [PDF]

open access: yes, 2018
PURPOSE To study if ovarian response is affected by the type of disease if fertility preservation is required. METHODS A registry of the trinational fertility preservation network FertiPROTEKT including 992 patients aged 18-40 years undergoing ...
T. Strowitzki   +7 more
core   +1 more source

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