Results 21 to 30 of about 215,664 (299)

PREMATURE OVARIAN INSUFFICIENCY IN SYSTEMIC SCLEROSIS

open access: yesAnti-Aging Eastern Europe, 2022
The early onset of ovarian aging results in decreased ovarian reserve and premature ovarian insufficiency (POI), leading to infertility and early menopause. POI is associated with systemic autoimmune diseases.
Neslihan Gokcen
doaj   +1 more source

Genetic features of platinum-resistant ovarian cancer patients [PDF]

open access: yes, 2014
Dubinina V. G., Rybin A. I., Mihailenko O. V., Kuznetsova O. V. Genetic features of platinum-resistant ovarian cancer patients. Journal of Health Sciences. 2014;4(14):50-56. ISSN 1429-9623 / 2300-665X.
Dubinina, V. G.   +3 more
core   +1 more source

MicroRNA in Ovarian Biology and Disease [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2015
MicroRNAs (miRNAs) are posttranscriptional gene regulatory molecules that show regulated expression within ovarian tissue. Most research investigating miRNAs in the ovary has relied exclusively on in vitro analyses. In this review, we highlight those few studies in which investigators have illustrated an in vivo effect of miRNAs on ovarian function. We
Lynda K, McGinnis   +2 more
openaire   +2 more sources

Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]

open access: yes, 2014
Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya   +4 more
core   +1 more source

Polyamines in Ovarian Aging and Disease

open access: yesInternational Journal of Molecular Sciences, 2023
Ovarian aging and disease-related decline in fertility are challenging medical and economic issues with an increasing prevalence. Polyamines are a class of polycationic alkylamines widely distributed in mammals. They are small molecules essential for cell growth and development.
Bo Kang   +7 more
openaire   +2 more sources

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk [PDF]

open access: yes, 2013
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were
Side, Lucy E.,   +999 more
core   +1 more source

Expression Regulation and Physiological Role of Transcription Factor FOXO3a During Ovarian Follicular Development

open access: yesFrontiers in Physiology, 2020
In mammals, developing ovarian follicles transform from primordial follicles to primary follicles, secondary follicles, and mature follicles, accompanied by changes in follicular secretory functions.
Hong Zhang   +4 more
doaj   +1 more source

Dual role for the unfolded protein response in the ovary: adaption and apoptosis

open access: yesProtein & Cell, 2016
The endoplasmic reticulum (ER) is the principal organelle responsible for several specific cellular functions including synthesis and folding of secretory or membrane proteins, lipid metabolism, and Ca2+ storage.
Ning Huang, Yang Yu, Jie Qiao
doaj   +1 more source

CA 125 Elevation: A Descriptive Etiological Study [PDF]

open access: yesNational Journal of Laboratory Medicine, 2016
Introduction: CA 125 (Cancer/Carbohydrate antigen 125) is a surface antigen expressed mostly by the ovarian cancer cells. Hence, it is widely used as a tumour marker for detection and monitoring the progression of such cancers.
Shaheena Appan Parambath   +6 more
doaj   +1 more source

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