Results 11 to 20 of about 561,797 (422)
Metabolic Cooperation in the Ovarian Follicle
Physiological Research, 2020 Granulosa cells (GCs) are somatic cells essential for establishing and maintaining bi-directional communication with the oocytes. This connection has a profound importance for the delivery of energy substrates, structural components and ions to the maturing oocyte through gap junctions.
T Žalmanová +4 more
openaire +4 more sources
Non-coding RNAs in the Ovarian Follicle [PDF]
Frontiers in Genetics, 2017 The mammalian ovarian follicle is the complex reproductive unit comprising germ cell, somatic cells (Cumulus and Granulosa cells), and follicular fluid (FF): paracrine communication among the different cell types through FF ensures the development of a mature oocyte ready for fertilization.
Battaglia, Rosalia +7 more
openaire +5 more sources
Bioengineering the Ovarian Follicle Microenvironment [PDF]
Annual Review of Biomedical Engineering, 2014 Chemo- and radiation therapies used to treat cancer can have the unintended effect of making patients infertile. Clinically established fertility preservation methods, such as egg and embryo cryopreservation, are not applicable to all patients, which has motivated the development of strategies that involve ovarian tissue removal and cryopreservation ...
Ariella Shikanov +2 more
openaire +4 more sources
Exosome-mediated communication in the ovarian follicle [PDF]
Journal of Assisted Reproduction and Genetics, 2016 Cells are able to produce and release different types of vesicles, such as microvesicles and exosomes, in the extracellular microenvironment. According to the scientific community, both microvesicles and exosomes are able to take on and transfer different macromolecules from and to other cells, and in this way, they can influence the recipient cell ...
C. Pietro
semanticscholar +6 more sources
The Signaling Pathways Involved in Ovarian Follicle Development. [PDF]
Front Physiol, 2021 The follicle is the functional unit of the ovary, which is composed of three types of cells: oocytes, granulosa cells, and theca cells. Ovarian follicle development and the subsequent ovulation process are coordinated by highly complex interplay between ...
Li L, Shi X, Shi Y, Wang Z.
europepmc +2 more sources
PLoS ONE, 2015 Mammalian target of rapamycin (mTOR) is a serine/threonine kinase and mTOR signaling is important in regulating cell growth and proliferation. Recent studies using oocyte- and granulosa cell-specific deletion of mTOR inhibitor genes TSC1 or TSC2 ...
Yuan Cheng +3 more
doaj +2 more sources
The ovarian follicle of ruminants: the path from conceptus to adult.
Reproduction, Fertility and Development, 2021 This review resulted from an international workshop and presents a consensus view of critical advances over the past decade in our understanding of follicle function in ruminants.
J. Juengel +9 more
semanticscholar +1 more source
Evaluation of inflammation and follicle depletion during ovarian ageing in mice
Scientific Reports, 2021 Reproductive ageing in females is defined by a progressive decline in follicle number and oocyte quality. This is a natural process that leads to the loss of fertility and ovarian function, cycle irregularity and eventually menopause or reproductive ...
Carolina Lliberós +5 more
semanticscholar +1 more source
Hydrogel Based 3-Dimensional (3D) System for Toxicity and High-Throughput (HTP) Analysis for Cultured Murine Ovarian Follicles. [PDF]
PLoS ONE, 2015 Various toxicants, drugs and their metabolites carry potential ovarian toxicity. Ovarian follicles, the functional unit of the ovary, are susceptible to this type of damage at all stages of their development.
Hong Zhou +4 more
doaj +1 more source
A modified hydrostatic microfluidic pumpless device for in vitro murine ovarian tissue culture as research model for fertility preservation [PDF]
Obstetrics & Gynecology Science, 2022 This study aimed to compare the efficacies of conventional and non-conventional (modified hydrostatic microfluidic pumpless device, MHPD) systems on ovarian tissue culture and in vitro follicle growth using a mouse model.
Paweena Thuwanut +5 more
doaj +1 more source