Results 41 to 50 of about 561,797 (422)

Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice

Stem Cell Research & Therapy, 2022
Background The massive loss of follicles in the early stage of ovarian tissue transplantation is considered a significant restriction to the efficacy of ovarian tissue cryopreservation (OTC) and transplantation (OT).
Jiaojiao Cheng, Xiangyan Ruan, Yanglu Li, Juan Du, Fengyu Jin, Muqing Gu, Qi Zhou, Xin Xu, Yu Yang, Husheng Wang, Alfred Otto Mueck   +10 more
doaj   +1 more source

Human Ovarian Follicles Xenografted in Immunoisolating Capsules Survive Long Term Implantation in Mice

Frontiers in Endocrinology, 2022
Female pediatric cancer survivors often develop Premature Ovarian Insufficiency (POI) owing to gonadotoxic effects of anticancer treatments. Here we investigate the use of a cell-based therapy consisting of human ovarian cortex encapsulated in a poly ...
Margaret A. Brunette, Hadrian M. Kinnear, Hadrian M. Kinnear, Prianka H. Hashim, Colleen L. Flanagan, James R. Day, Marilia Cascalho, Marilia Cascalho, Vasantha Padmanabhan, Vasantha Padmanabhan, Ariella Shikanov, Ariella Shikanov, Ariella Shikanov   +12 more
doaj   +1 more source

In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling [PDF]

, 2014
STUDY QUESTION How does maternal cigarette smoking disturb development of the human fetal ovary?<p></p> SUMMARY ANSWER Maternal smoking increases fetal estrogen titres and dysregulates several developmental processes in the fetal ovary.<
A. J. Childs, A. MacKenzie, A. Maheshwari, A. Monteiro, Anderson, Arnold, B. Le Bizec, Baker, Bernstein, Birney, Childs, Childs, Courant, Coutts, F. Courant, F. Evans, George, Holl, Hoover, J.-P. Antignac, Jensen, Jensen, Jensen, Josiak, Laissue, Lechowska, Martins da Silva, Matikainen, P. A. Fowler, P. Filis, P. J. O'Shaughnessy, Pepe, Prabhu, R. A. Anderson, Roy, S. Bhattacharya, S. Flannigan, S. M. Rhind, SHUTT, Smith, Tang, Tappin, Toriola, van den Driesche, Wallace, WEINBERG, Werler, Xing, Zachos, Zhuang   +49 more
core   +2 more sources

Three-dimensional organization of transzonal projections and other cytoplasmic extensions in the mouse ovarian follicle

Scientific Reports, 2019
Each mammalian oocyte is nurtured by its own multi-cellular structure, the ovarian follicle. We used new methods for serial section electron microscopy to examine entire cumulus and mural granulosa cells and their projections in mouse antral ovarian ...
V. Baena, M. Terasaki
semanticscholar   +1 more source

Ovarian function during hormonal contraception assessed by endocrine and sonographic markers: a systematic review [PDF]

, 2016
This systematic review focuses on the literature evidence for residual ovarian function during treatment with hormonal contraceptives. We reviewed all papers which assessed residual ovarian activity during hormonal contraceptive use, using endocrine ...
Bastianelli, Carlo, Candelieri, Miriam, D'Arpe, Stella, DI FELICIANTONIO, Mara, Franceschetti, Silvia, Piccioni, Maria Grazia   +5 more
core   +1 more source

Ovarian Follicle Depletion Induced by Chemotherapy and the Investigational Stages of Potential Fertility-Protective Treatments—A Review

International Journal of Molecular Sciences, 2019
Ovarian follicle pool depletion, infertility, and premature menopause are all known sequelae of cancer treatment that negatively impact the quality of life of young cancer survivors.
X. Hao, A. Anastácio, Kui Liu, K. Rodriguez-Wallberg   +3 more
semanticscholar   +1 more source

Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats [PDF]

, 2012
We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function ...
Abbott, Abbott, Abbott, Alan S McNeilly, Amanda J Drake, Anderson, Anderson, Baravalle, BARRACLOUGH, Beloosesky, BRAWER, Brawer, Carretero, Champagne, Childs, Durlinger, Faiman, Franks, Grossmann, Hillier, HIRSHFIELD, Hoepfner, Honnma, Levallet, Marie Broyde, McNeilly, Michelle Welsh, Misugi, Murray, Nelson, Nelson, Nilsson, Ota, Pepling, Pepling, Picon, Rey, Richard Sharpe, Roma, Rossetti, Scalzo, Schindler, Slob, Tetsuka, Victoria Tyndall, Webber, Welsh, Welsh, Wolf, Xia, Yan   +50 more
core   +3 more sources

Effect of mercury vapor inhalation on rat ovary: stereology and histopathology [PDF]

, 2016
AimMercury, an environmental contaminant, is a risk factor for health in whole living organisms. In this study, we investigated whether mercury vapor (HgO) inhalation has an effect on rat ovary.
Akgul, Hayati Murat, Akgul, Nilgun, Altunkaynak, Berrin Zuhal, Altunkaynak, Muhammed Eyup, Turkmen, Aysin Pinar, Unal, Bunyami, Yahyazedeh, Ahmad   +6 more
core   +1 more source

Female reproductive aging is master-planned at the level of ovary.

PLoS ONE, 2014
The ovary receives a finite pool of follicles during fetal life. Atresia remains the major form of follicular expenditure at all stages since development of ovary.
Sayani Banerjee, Sutapa Banerjee, Ghungroo Saraswat, Soma Aditya Bandyopadhyay, Syed N Kabir   +4 more
doaj   +1 more source

Proliferating cell nuclear antigen (PCNA) allows the automatic identification of follicles in microscopic images of human ovarian tissue [PDF]

Pathology and Laboratory Medicine International 2010:2; 99-105, 2010
Human ovarian reserve is defined by the population of nongrowing follicles (NGFs) in the ovary. Direct estimation of ovarian reserve involves the identification of NGFs in prepared ovarian tissue. Previous studies involving human tissue have used hematoxylin and eosin (HE) stain, with NGF populations estimated by human examination either of tissue ...
arxiv   +1 more source