Results 71 to 80 of about 107,481 (307)
Advanced Science, EarlyView.This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo +10 more
wiley +1 more source
Ovarian follicle burnout: A universal phenomenon? [PDF]
Cell Cycle, 2013 The ovarian follicle reserve is maintained in a delicate state of homeostasis aimed at preserving the majority of follicles in a dormant state. Key regulatory factors in follicle activation and quiescence include the PI3K/PTEN/Akt signaling pathway in the oocyte, as well as external paracrine inhibitory factors such as anti-Mullerian hormone (AMH) (Fig.
Roness, Hadassa +3 more
openaire +2 more sources
Regulation of the G2/M Transition in Rodent Oocytes [PDF]
, 2010 Regulation of maturation in meiotically competent mammalian oocytes is a complex process involving the carefully coordinated exchange of signals between the somatic and germ cell compartments of the ovarian follicle via paracrine and cell–cell coupling ...
Downs, Stephen
core +2 more sources
Advanced Science, EarlyView.CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu +13 more
wiley +1 more source
Advances in methods for determining fecundity: application of the new methods to some marine fishes [PDF]
, 2009 Estimation of individual egg production (realized fecundity) is a key step either to understand the stock and recruit relationship or to carry out fisheries-independent assessment of spawning stock biomass using egg production methods.
Dominguez, Rosario +7 more
core
Foliculogénesis Ovárica en la Raya Marmorada, Sympterygia bonapartii (Müller & Henle, 1841) (Chondrichthyes, Rajidae) [PDF]
, 2011 Los Condrictios se han convertido en un recurso económico importante en las últimas décadas, siendo Argentina uno de los países que más explota tiburones y rayas, incluso a niveles que exceden los límites de varias especies.
Díaz Andrade, María Constanza +3 more
core +1 more source
Advanced Science, EarlyView.This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley +1 more source
Regulation of reproduction via tight control of gonadotropin hormone levels. [PDF]
, 2018 Mammalian reproduction is controlled by the hypothalamic-pituitary-gonadal axis. GnRH from the hypothalamus regulates synthesis and secretion of gonadotropins, LH and FSH, which then control steroidogenesis and gametogenesis. In females, serum LH and FSH
Coss, Djurdjica
core +1 more source
Advanced Science, EarlyView.Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Iranian South Medical Journal, 2016 Background: Ovarian reserve tests have appeared as important, useful and new tools in evaluation of infertile women and by doing these tests, we can do for infertile couples advanced and necessary measures quickly.
Elham Rahmani +3 more
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