Results 1 to 10 of about 5,436,969 (234)
Journal of Biomedical Science, 2021 Objective Researchers have revealed the combined functions of long noncoding RNAs (lncRNAs) and microRNA (miRNAs) in polycystic ovary syndrome (PCOS). This study aimed to understand the role of nuclear-enriched abundant transcript 1 (NEAT1) and miR-381 ...
Jingran Zhen +6 more
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Frontiers in Endocrinology, 2023 ObjectiveThe aim of this study was to explore the symptoms, treatment, and pathogenesis of ovarian juvenile granulosa cell tumors with Ollier’s disease in children.MethodsFrom October 2019 to October 2020, clinical data were retrospectively analyzed for ...
Jin Zhang +7 more
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Biological Research, 2023 Background The main features of polycystic ovary syndrome (PCOS) are abnormal follicular development and ovulatory dysfunction, which are caused by excessive apoptosis of ovarian granulosa cells.
Xiaohong Chen +8 more
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Granulosa Cell Tumour – A Rare Presentation at Age Twenty
Pakistan Journal of Medicine and Dentistry, 2020 Granulosa cell tumor is a rare type of ovarian tumor, which arises from sex cord stroma. Histologically this tumor has two types and is named according to the common age group they affect; adult granulosa cell tumor (AGCT) and juvenile granulosa cell ...
Munazza Ani +4 more
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Gynecological Endocrinology, 2023 Objective Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a major cause of infertility in female worldwide. Excessive apoptosis and impaired autophagy in ovarian granulosa cells are the main pathological mechanisms of POF.
Weimei Zhou +6 more
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Cells, 2022 Our previous study demonstrated that ovarian wild-type P53-induced phosphatase 1 (WIP1) expression decreased with age. We hypothesized that WIP1 activity was related to ovarian aging. The role of WIP1 in regulating ovarian aging and its mechanisms remain
Su Zhou +9 more
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Journal of Animal Reproduction and Biotechnology, 2016 The purpose of this study was to examine the effects of taurine and vitamin E on ovarian granulosa cells damaged by bromopropane (BP) in pigs. We evaluated cell viability, plasma membrane integrity (PMI) and apoptotic morphological change in porcine ...
Seunghyung Lee +5 more
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Sclerosing Peritonitis Occurring in Association with Juvenile Granulosa Cell Tumour – A Cause of Concern [PDF]
Journal of Clinical and Diagnostic Research, 2014 Sclerosing Peritonitis (SP) is characterized by fibrous thickening and adhesions of the peritoneum and it is encountered frequently in association with peritoneal dialysis, practolol and anticonvulsant therapy. Rarely does it present as a gynaecological
Amita K. +3 more
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Role of COX-2/PGE2 signaling pathway in the apoptosis of rat ovarian granulosa cells induced by MEHP
Ecotoxicology and Environmental Safety, 2023 Objective: MEHP, as the metabolite of DEHP, is a widely used environmental endocrine disruptor. Ovarian granulosa cells participate in maintaining the function of ovary and COX2/PGE2 pathway may regulate the function of granulosa cells.
Xu Li +9 more
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Germ–Somatic Cell Interactions Are Involved in Establishing the Follicle Reserve in Mammals
Frontiers in Cell and Developmental Biology, 2021 Mammalian females are born with a finite reserve of ovarian follicles, the functional units of the ovary. Building an ovarian follicle involves a complex interaction between multiple cell types, of which the oocyte germ cell and the somatic granulosa ...
Patrícia Rodrigues +7 more
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