Results 201 to 210 of about 5,004,988 (242)
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OVARIAN GRANULOSA CELL TUMOR AND ACROMEGALY
The Journal of Clinical Endocrinology & Metabolism, 1949AMENORRHEA is one of the most consistent and usually one of the earliest symptoms of pituitary tumor in women. Menstrual function may return, however, even after a prolonged period of amenorrhea, following surgical removal of the tumor, its shrinkage by roentgen irradiation, or possibly in rare instances following the escape of the expanding tumor from
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Emerging biomarkers in ovarian granulosa cell tumors
International Journal of Gynecological Cancer, 2019Although the majority of ovarian granulosa cell tumors can be successfully managed with surgery, a subset require chemotherapy for residual and recurrent disease. The benefit of chemotherapy in this population, however, remains controversial. There is therefore interest in the development of more tolerable and effective treatment options for advanced ...
Anne M, Mills +6 more
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Effect of Doxorubicin-Induced Ovarian Toxicity on Mouse Ovarian Granulosa Cells
Regulatory Toxicology and Pharmacology, 2017The objective of this study was to identify the effect of doxorubicin-induced ovarian toxicity on mouse ovarian granulosa cells. After granulosa cells were treated with doxorubicin at the final concentrations of 0, 0.4, 0.8, and 1.6 μg/ml for 24 h, cell apoptosis was detected by DAPI staining or caspase-3/7 fluorescence probe; ROS was determined by 2',
Ting Zhang
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The distribution of actin in cultured ovarian granulosa cells
American Journal of Anatomy, 1983AbstractOvarian granulosa cells grown on glass coverslips were split by a “sandwich” technique. Using this technique we describe a complex filamentous network in the cytoplasm of cultured granulosa cells that was composed of a branching and anastomosing lattice of filaments 20–40 nm in diameter.
B E, Batten, E, Anderson
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Coordinated Receptor Regulation in Ovarian Granulosa Cells
1987The concept of receptor down regulation by its own hormone through internalization of the hormone-receptor complex is well established (for reviews, see Blecher and Bar, 1981; Kaplan, 1981). However, the cellular basis for heterologous receptor regulation is less well defined.
T T, Chen +3 more
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Ovarian granulosa cell proliferations of pregnancy: A report of nine cases
Human Pathology, 1988Granulosa cell proliferations that simulated small neoplasms were incidental findings in the ovaries of nine pregnant women. The lesions were typically multiple and associated with atretic follicles. In eight cases, the granulosa cells were arranged in solid, insular, microfollicular, and trabecular patterns, but in the ninth case, there was a ...
P B, Clement, R H, Young, R E, Scully
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Ovarian juvenile granulosa cell tumors
Adolescent and Pediatric Gynecology, 1990Abstract Ovarian neoplasms, though rarely seen in children or adolescents, are very important biologically due to their potential to affect growth, development, and fertility in these patients; therefore, prompt diagnosis is imperative. Ovarian juvenile granulosa cell tumors (JGCT) occur predominantly in the first two decades of life.
Charles V. Biscotti +1 more
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Granulosa-thecal cell interaction in ovarian steroidogenesis
Journal of Steroid Biochemistry, 1979Abstract 1. 1. It is clear from all studies of follicles in many species that the theca under LH control favors androgen production and the granulosa stimulated by FSH favors aromatization. This is consonant with synergism of FSH and LH in follicle development and the synergism of the two cells in oestrogen production. 2. 2.
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Immunohistochemical differentiation between ovarian granulosa cell tumors and ovarian carcinomas
Archives of Gynecology and Obstetrics, 1991Differential diagnosis is a major problem in histopathology of ovarian tumors. Difficulties may arise if the tumor is a poorly differentiated carcinoma or a granulosa cell tumor of the sarcomatoid type. It was the aim of the present study to evaluate the usefulness of immunohistochemistry in differentiating between granulosa cell tumors of the ovary ...
G, Gitsch +4 more
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Survival after Ovarian Granulosa and Theca Cell Tumours
Scottish Medical Journal, 1987Ninety-two cases of ovarian granulosa and theca cell tumours were recorded in the Tayside Gynaecological Tumour Registry during the 30 year period 1948–78. A high follow-up rate was achieved through this centralised registry and exhaustive annual recall.
J, Dempster, R T, Geirsson, I D, Duncan
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