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A mouse tool for conditional mutagenesis in ovarian granulosa cells
genesis, 2010AbstractHere we describe the generation of an inducible Cre transgenic line allowing conditional mutagenesis in ovarian granulosa cells. We have expressed the tamoxifen inducible CreERT2 fusion protein from a Bacterial Artificial Chromosome (BAC) containing the regulatory elements of the hydroxysteroid (17‐beta) dehydrogenase 1 (Hsd17b1) gene.
Beatrice, Grabner +6 more
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The cytoplasmic filamentous network in cultured ovarian granulosa cells
Cell, 1980We have utilized a cracking procedure followed by a rotary shadow technique to examine the ultrastructure of cultured ovarian granulosa cells. We have demonstrated that the structures observed are not artifacts of fixation or cracking by generating equivalent images following freezing and deep etching as well as by fixation prior to cracking.
B E, Batten, J J, Aalberg, E, Anderson
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Effects of capsaicin on ovarian granulosa cell proliferation and apoptosis
Cell and Tissue Research, 2018Capsaicin is the pungent ingredient in red peppers. Due to the effects on the sensory nerve fibers, capsaicin has been used to treat pain and inflammation associated with a variety of diseases including rheumatoid arthritis and diabetic neuropathy, obesity, and cardiovascular and gastrointestinal conditions.
ZIK, BERRİN, GÜLER, SABİRE
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Steroid Biosynthesis by Human Ovarian Granulosa and Thecal Cells
The Journal of Clinical Endocrinology & Metabolism, 1966The separation of granulosa cells from thecal elements of the human ovarian follicle has been described. The 2 cell types were incubated in vitro with progesterone-4-14C and pregnenolone-7-3H. Steroid metabolites were isolated with each of the cell types and crystallized to constant specific activity.
K J, Ryan, Z, Petro
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Morphological variations in gap junctions of ovarian granulosa cells
Tissue and Cell, 1975Granulosa cells in ovarian follicles of rat, mouse, rabbit and hamster were studied by lanthanum tracer and freeze-fracture techniques. Abundant gap junctions exhibited striking intraspecific variation in size and pattern of particle aggregation. The smaller gap junctions showed close packing of the intramembranous A face particles.
D F, Albertini, D W, Fawcett, P J, Olds
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MicroRNA Expression is Altered in Granulosa Cells of Ovarian Hyperresponders
Reproductive Sciences, 2016Controlled ovarian stimulation plays an integral role in assisted reproduction technology, but individual patients have different responses to exogenous gonadotropins. In order to determine whether microRNAs (miRNAs) have a regulatory role in ovarian response, we profiled the expression of microRNAs in isolated ovarian granulosa cells collected from ...
Shi, Xie +3 more
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Methods for Evaluation of Ovarian Granulosa Cells with Exposure to Nanoparticles
2018Increasing evidence demonstrates that a substantial number of chemicals including nanoparticles have potential toxic effects on human and wildlife reproductive health. Ovarian granulosa cells (GCs), the functional unit of the ovary, play a pivotal role in the regulation of ovarian reproductive health in females.
Jin, Liu, Wenchang, Zhang
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[Recurrences of ovarian granulosa cell tumors].
Arkhiv patologii, 1978Investigations of two cases of relapses of granulocellular tumors of the ovaries established their characteristics: cyst formation in nodes of the tumor growing on the peritoneum, formation of Call-Exner strucutres characteristic of the ovary tissue in tumors, and growth of the tumor on serous integument without ingrowing into the parenchyma of the ...
M A, Sapozhnikova, V S, Tebenikhin
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Autophagy Regulates Differentiation of Ovarian Granulosa Cells Through Degradation of WT1
Autophagy, 2022Zi-Jiang Chen, Shidou Zhao, Yingying Qin
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