Results 211 to 220 of about 49,951 (251)

OVARIAN GRANULOSA CELL TUMOR AND ACROMEGALY

The Journal of Clinical Endocrinology & Metabolism, 1949
AMENORRHEA is one of the most consistent and usually one of the earliest symptoms of pituitary tumor in women. Menstrual function may return, however, even after a prolonged period of amenorrhea, following surgical removal of the tumor, its shrinkage by roentgen irradiation, or possibly in rare instances following the escape of the expanding tumor from
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Coordinated Receptor Regulation in Ovarian Granulosa Cells

1987
The concept of receptor down regulation by its own hormone through internalization of the hormone-receptor complex is well established (for reviews, see Blecher and Bar, 1981; Kaplan, 1981). However, the cellular basis for heterologous receptor regulation is less well defined.
T T, Chen, K, Gao, M A, Shelton, D D, Hatmaker   +3 more
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Purification of granulosa cells from human ovarian follicular fluid using granulosa cell aggregates

Reproduction, Fertility and Development, 2006
Human follicular fluid can provide a source of human granulosa cells for scientific study. However, removing potentially contaminating cells, such as white and red blood cells, is important for molecular and in vitro studies. We have developed a purification technique for human granulosa cells based on the selection of cellular aggregates.
M C J, Quinn, S B, McGregor, J L, Stanton, P A, Hessian, W R, Gillett, D P L, Green   +5 more
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Immunohistochemical differentiation between ovarian granulosa cell tumors and ovarian carcinomas

Archives of Gynecology and Obstetrics, 1991
Differential diagnosis is a major problem in histopathology of ovarian tumors. Difficulties may arise if the tumor is a poorly differentiated carcinoma or a granulosa cell tumor of the sarcomatoid type. It was the aim of the present study to evaluate the usefulness of immunohistochemistry in differentiating between granulosa cell tumors of the ovary ...
G, Gitsch, P, Kohlberger, E, Hanzal, H, Kölbl, G, Breitenecker   +4 more
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The function of exosomes in ovarian granulosa cells

Cell and Tissue Research, 2023
Granulosa cells (GCs), as the basic components of ovarian tissue, play an indispensable role in maintaining normal ovarian functions such as hormone synthesis and ovulation. The abnormality of GCs often leads to ovarian endocrine disorders, which exert a negative effect on life quality and life expectancy.
Ruotong Zhou, Dan Liu
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Granulosa-thecal cell interaction in ovarian steroidogenesis

Journal of Steroid Biochemistry, 1979
Abstract 1. 1. It is clear from all studies of follicles in many species that the theca under LH control favors androgen production and the granulosa stimulated by FSH favors aromatization. This is consonant with synergism of FSH and LH in follicle development and the synergism of the two cells in oestrogen production. 2. 2.
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Survival after Ovarian Granulosa and Theca Cell Tumours

Scottish Medical Journal, 1987
Ninety-two cases of ovarian granulosa and theca cell tumours were recorded in the Tayside Gynaecological Tumour Registry during the 30 year period 1948–78. A high follow-up rate was achieved through this centralised registry and exhaustive annual recall.
J, Dempster, R T, Geirsson, I D, Duncan
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Prognostic factors in ovarian adult granulosa cell tumour

Journal of Clinical Pathology, 2008
Ovarian granulosa cell tumours are relatively uncommon sex-cord–stromal neoplasms that account for approximately 1–2% of all ovarian malignancies. They are of adult or juvenile type, the former being more common. The prognosis of juvenile granulosa cell tumour (JGCT) is excellent, with tumour recurrence or metastasis being rare, although when this ...
Keith, Miller, W Glenn, McCluggage
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Therapy of Advanced Ovarian Juvenile Granulosa Cell Tumors

Klinische Pädiatrie, 2002
Gonadal sex cord-stromal tumors are rare tumors that develop from the gonadal non-germ cell component such as granulosa, Sertoli or Leydig cells. Among these, juvenile granulosa cell tumors (JGCT) constitute the largest subgroup of ovarian sex cord-stromal tumors during childhood and adolescence.
D T, Schneider, G, Calaminus, R, Wessalowski, R, Pathmanathan, D, Harms, U, Göbel   +5 more
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Monosomy 22 in two ovarian granulosa cell tumors

Cancer Genetics and Cytogenetics, 1996
Cytogenetic studies of ovarian sex cord stromal cell tumors, although limited in number, have found trisomy 12 to be a recurring abnormality, especially in fibromas and granulosa cell tumors (GCTs). However, recent fluorescence in situ hybridization (FISH) studies have failed to confirm a high prevalence of trisomy 12 in GCTs.
V, Lindgren, S, Waggoner, J, Rotmensch
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