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Postoperative chemotherapy in advanced ovarian granulosa cell tumors
International Journal of Gynecological Cancer, 2002The objective of this research is to assess the use of first-line postoperative chemotherapy in patients with advanced ovarian granulosa cell tumor (GCT). A retrospective population-based case series identified 60 women with stage IC or greater ovarian GCT over a 25-year period. Five patients were excluded because of incomplete information. None of the
I A, Al-Badawi +5 more
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Declining ovarian reserve adversely influences granulosa cell viability
Fertility and Sterility, 2007To identify if declining ovarian reserve adversely influences granulosa cell (GC) parameters in patients undergoing IVF.Prospective study.Academic IVF Center.Twenty-four women undergoing IVF.Mural and cumulus GCs were harvested (at time of egg retrieval).Influence of ovarian reserve, reflected by maximal basal FSH levels, on GC (cumulative, mural, and ...
Keri, Greenseid +5 more
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[Recurrences of ovarian granulosa cell tumors].
Arkhiv patologii, 1978Investigations of two cases of relapses of granulocellular tumors of the ovaries established their characteristics: cyst formation in nodes of the tumor growing on the peritoneum, formation of Call-Exner strucutres characteristic of the ovary tissue in tumors, and growth of the tumor on serous integument without ingrowing into the parenchyma of the ...
M A, Sapozhnikova, V S, Tebenikhin
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Genistein effect in cultured ovine ovarian granulosa cells
Journal of Biochemical and Molecular ToxicologyAbstractGenistein, an isoflavone has the potential to mimic, augment, or dysregulate the steroid hormone production pathways. We hypothesized that genistein affects the granulosa cell (GCs) functions through a series of biochemical, molecular, and genomic cascades.
Poonam K. Singh +4 more
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Decreased FTO Expression Promotes Ovarian Granulosa Cells Aging
Reproductive SciencesThis study aimed to investigate the role of fat mass and obesity-associated protein (FTO), an N6-methyladenosine (m6A) demethylase, in ovarian aging by examining the effects of FTO downregulation on key biological processes in human ovarian granulosa cells (KGN), including proliferation, apoptosis regulation, senescence, and steroidogenic function ...
Jia Ying +3 more
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Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1
Autophagy, 2022Ran Liu, Xue Jiao, Wei Li
exaly