Results 31 to 40 of about 5,004,988 (242)

Effect of oxytocin on free intracellular Ca2+ levels and progesterone release by human granulosa-lutein cells [PDF]

, 1993
Oxytocin and its receptor are found in the corpus luteum in a variety of species, including the human. In the present study we used fura-2 microfluorimetry to investigate whether activation of the oxytocin receptor of cultured human granulosa-lutein ...
Wiemann, M., Link, H., Sterzik, K., Gratzl, Manfred, Mayerhofer, Artur   +4 more
core   +1 more source

Elevated SAA1 promotes the development of insulin resistance in ovarian granulosa cells in polycystic ovary syndrome

Reproductive Biology and Endocrinology, 2022
Background Insulin resistance (IR) contributes to ovarian dysfunctions in polycystic ovarian syndrome (PCOS) patients. Serum amyloid A1 (SAA1) is an acute phase protein produced primarily by the liver in response to inflammation.
Qinling Zhu, Yue Yao, Lizhen Xu, Hasiximuke Wu, Wangsheng Wang, Yaqiong He, Yuan Wang, Yao Lu, Jia Qi, Ying Ding, Xinyu Li, Jiaan Huang, Hanting Zhao, Yanzhi Du, Kang Sun, Yun Sun   +15 more
doaj   +1 more source

Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells : Implications for luteolysis [PDF]

, 2009
The human LH receptor (LHR) plays a key role in luteal function and the establishment of pregnancy through its interaction with the gonadotropins LH and human chorionic gonadotropin.
Dickinson, Rachel E, Myers, Michelle, Duncan, W Colin, Stewart, Alan J., Millar, Robert P, Stewart, Alan J.; id_orcid   +5 more
core   +1 more source

Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner

Journal of Ovarian Research, 2020
Background The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its
Yoko Urata, Reza Salehi, Patricia D. A. Lima, Yutaka Osuga, Benjamin K. Tsang   +4 more
doaj   +1 more source

Nuclear Receptor Profiling of Ovarian Granulosa Cell Tumors [PDF]

Hormones and Cancer, 2011
Granulosa cell tumors of the ovary (GCT) represent ~5% of malignant ovarian tumors. The adult form is defined by a mutation in the FOXL2 gene. GCT exhibit many of the features of normal proliferating granulosa cells. We have profiled the expression of the 48 human nuclear receptors (NR) by quantitative RT-PCR in a panel of GCT and in two GCT-derived ...
Alexiadis, Maria, Eriksson, Natalie, Jamieson, Stacey, Davis, Melissa, Drummond, Ann E., Chu, Simon, Clyne, Colin D., Muscat, George E., Fuller, Peter J.   +8 more
openaire   +4 more sources

Ovarian Granulosa Cell Genomics in PCOS .zip

, 2023
To investigate gene expression in ovarian granulosa cells by using high-throughput gene sequencing and to investigate pathogenesis in phlegm wet polycystic ovary syndrome (PCOS) patients using functional and pathway analyses. 
shuai zhao (14793550)
core   +1 more source

Displaced granulosa cells in peritoneal washings : a rare diagnostic pitfall [PDF]

, 2011
Developing follicles and follicular cysts in the ovary\ud are lined by granulosa cells. Approximately the size of\ud histiocytes, non-neoplastic granulosa cells have scant\ud granular to foamy cytoplasm and mildly atypical\ud hyperchromatic nuclei, which
Ribu, D. L., Shield, P. W., Cominos, D.
core   +1 more source

Supplemental Materials_Wang et al Organophosphate Esters Disrupt Steroidogenesis in KGN Human Ovarian Granulosa Cells

, 2023
This flie is the supplemental materials for publication Wang et al Organophosphate Esters Disrupt Steroidogenesis in KGN Human Ovarian Granulosa Cells, Endocrinology, 2023;, bqad089, https://doi.org/10.1210/endocr ...
Xiaotong Wang, Elaine Lee, Barbara F Hales, Bernard Robaire
core   +1 more source

Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity

Cell Death and Disease, 2022
Endometriosis (EMs) occurs in approximately 50% of women with infertility. The main causes of EMs-related infertility are follicle dysplasia and reduced oocyte quality.
Zhexin Ni, Yangshuo Li, Di Song, Jie Ding, Shanshan Mei, Shuai Sun, Wen Cheng, Jin Yu, Ling Zhou, Yanping Kuang, Mingqing Li, Zailong Cai, Chaoqin Yu   +12 more
doaj   +1 more source

Ovarian juvenile granulosa cell tumors with Ollier’s disease in children with IDH1 gene somatic mutation

Frontiers in Endocrinology, 2023
ObjectiveThe aim of this study was to explore the symptoms, treatment, and pathogenesis of ovarian juvenile granulosa cell tumors with Ollier’s disease in children.MethodsFrom October 2019 to October 2020, clinical data were retrospectively analyzed for ...
Jin Zhang, Renwu Hua, Lishuang Ma, Chao Liu, Yanxia Zhang, Xuemin Lü, Tianren Wang, Naijun Wan   +7 more
doaj   +1 more source