Results 11 to 20 of about 5,004,988 (242)

Granulosa Cells: Central Regulators of Female Fertility

open access: yesEndocrines
Background: Granulosa cells are somatic cells within the ovarian follicle. As the primary site of estradiol production, they are critical regulators of several aspects of female reproduction.
Luis Fernando Schütz   +1 more
doaj   +2 more sources

Overexpression of CDC25C affects the cell cycle of ovarian granulosa cells from adult and young goats [PDF]

open access: yesElectronic Journal of Biotechnology, 2018
Background: CDC25 is a dual-specificity phosphatase that was first identified in the yeast Schizosaccharomyces pombe as a cell cycle-defective mutant. Although CDC25 is involved in the cell cycle of ovarian granulosa cells, the CDC25 signaling pathway ...
Haiyan Guo   +5 more
doaj   +3 more sources

Follicle-stimulating hormone is expressed in ovarian follicles of chickens and promotes ovarian granulosa cell proliferation

open access: yesJournal of Integrative Agriculture, 2021
Follicle-stimulating hormone (FSH), an important hypothalamic-pituitary-gonadal axis (HPG) hormone, is secreted by the pituitary gland. This study confirms that FSH is expressed in chicken follicles at different stages, and positive FSHβ mRNA signals ...
Yu-lin BI   +4 more
doaj   +2 more sources

Dietary Glycotoxins, Advanced Glycation End Products, Inhibit Cell Proliferation and Progesterone Secretion in Ovarian Granulosa Cells and Mimic PCOS-Like Symptoms

open access: yesBiomolecules, 2019
Women with polycystic ovary syndrome (PCOS) have been reported to have an elevated serum advanced glycation end product (AGE) level. However, the effect of AGEs on the pathophysiological ovarian granulosa cells of PCOS is still unclear.
Po-Han Lin   +10 more
doaj   +2 more sources

Protective effect of luteinizing hormone on frozen-thawed ovarian follicles and granulosa cells.

open access: yesPLoS ONE
Ovarian tissue cryopreservation addresses critical challenges in fertility preservation for prepubertal female cancer patients, such as the lack of viable eggs and hormonal deficiencies.
Jie Chen   +4 more
doaj   +2 more sources

Advances in the Effects of Heat Stress on Ovarian Granulosa Cells: Unveiling Novel Ferroptosis Pathways

open access: yesVeterinary Sciences
Heat stress has been one of the key research areas for researchers due to the wide-ranging effects and complex mechanisms of action of its stress product reactive oxygen species (ROS).
Zhen Zhu   +6 more
doaj   +2 more sources

Ovarian Granulosa Cell Tumor: A Clinicopathological Series [PDF]

open access: yesObstetrics and Gynaecology Cases - Reviews, 2018
Introduction: Granulosa cell tumours (GCT) are uncommon neoplasms, accounting for 2-5% of all ovarian carcinomas. The pathogenesis of these tumours is characterised by differentiation towards the follicular granulosa cell. However, the exact cell of origin is disputed, with the granulosa cell, thecal cell or fibroblast having been proposed as putative ...
Brincat, Mark R.   +8 more
openaire   +2 more sources

Renal metastasis of ovarian granulosa cell tumor

open access: yesIJU Case Reports, 2022
IntroductionWe would like to present a rare case of metastatic renal tumor.Case presentationA 60‐year‐old woman presented to our department with a left renal tumor. She underwent a total hysterectomy and right adnexal resection for a stage IA ovarian granulosa cell tumor approximately 15 years ago, followed by left adnexal resection and postoperative ...
Kyo Togashi   +8 more
openaire   +3 more sources

The molecular mechanism of ovarian granulosa cell tumors [PDF]

open access: yesJournal of Ovarian Research, 2018
Over these years, more and more sex cord-stromal tumors have been reported. Granulosa cell tumor (GCT) is a rare tumor in ovaries, accounts for 2% to 5% of ovarian cancers. The main different feature of GCTs from other ovarian cancers is that GCTs can lead to abnormally secreted hormones (estrogen, inhibin and Müllerian inhibiting substance).
Jiaheng Li   +3 more
openaire   +3 more sources

Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]

open access: yes, 2014
Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya   +4 more
core   +1 more source

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