Results 81 to 90 of about 5,004,988 (242)

USP14 inhibition promotes DNA damage repair and represses ovarian granulosa cell senescence in premature ovarian insufficiency

Journal of Translational Medicine
Background Premature ovarian insufficiency (POI) is a condition characterized by a substantial decline or loss of ovarian function in women before the age of 40.
Lin-Zi Ma, Ao Wang, Yun-Hui Lai, Jun Zhang, Xiao-Fei Zhang, Shi-Ling Chen, Xing-Yu Zhou   +6 more
doaj   +1 more source

Peroxiredoxin 4 protects against ovarian ageing by ameliorating d-galactose-induced oxidative damage in mice

Cell Death and Disease, 2020
Peroxiredoxin 4 (Prdx4), a member of the Prdx family, is a vital ER-resident antioxidant in cells. As revealed in our previous study, Prdx4 expression was detected in ovarian granulosa cells and was closely related to ovarian function.
Xiuru Liang, Zhengjie Yan, Weiwei Ma, Yi Qian, Xiaofei Zou, Yugui Cui, Jiayin Liu, Yan Meng   +7 more
doaj   +1 more source

Mechanisms of and Potential Medications for Oxidative Stress in Ovarian Granulosa Cells: A Review

, 2023
Granulosa cells are essential for follicle initiation and development, and their abnormal function or apoptosis is a crucial factor leading to follicular atresia.
Siheng Liu, Yiran Luo, Yunbing Jia, Qi Yang, Shirui Meng, Zezheng Pan   +5 more
core   +1 more source

Association Between Blood Transfusion for Postpartum Haemorrhage and the Risk of Premature Ovarian Failure: A Nationwide Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate the association between postpartum haemorrhage (PPH) severity and the subsequent risk of premature ovarian failure (POF), with blood transfusion used as a marker of severe PPH: Design Nationwide population‐based retrospective cohort study. Setting Korean National Health Insurance Service (KNHIS) database.
Min‐A Kim, Ju Hyeong Son, Hyun‐Joo Seol, Min‐Jeong Oh, Geum Joon Cho, Young‐Han Kim   +5 more
wiley   +1 more source

Apoptosis of granulosa cell.

, 2018
A. Flow cytometry analysis was performed to measure the apoptotic status of granulosa cell. B. Compared with control group, the apoptotic rate of ovarian granulosa cells in POF, CH +, CH ++ and CH +++ groups was significantly higher ...
YaXin Hu (5586848), Lei Yu (70258), YongMei Liu (5586851), Ming-liang Cheng (5586857), Xinyan Liu (385724), Zhuo Cheng (747969), Bao-fang Zhang (5586845), Yu Lei (266919), Xueke Zhao (5586854), Mao Mu (3375368)   +9 more
core   +1 more source

Identification of ovarian granulosa cells and effect examination

, 2020
Figure S1. Identification of ovarian granulosa cells. Figure S2. The mensuration of over-expression effect. (A: The relative mRNA level of over-expression MT1, MT2, Cry1, and Cry2 at 24h by Q-PCR; B: Western blotting (WB) results of MT1, MT2, CRY1, and ...
Zhao Shu-Qin, Zhao Shu-Qin (8327931)
core   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

The human ovarian granulosa cell: a stereological approach.

Journal of anatomy, 1996
The human ovarian granulosa cell is perhaps the most widely studied endocrine cell, but little quantitative structural information exists for this cell. In the present study new and traditional stereological probes have been employed to provide quantitative structural information on these functionally important cells. Granulosa cells were obtained from
O, WS, Dhar, A, Dockery, P, Turner, K, Lenton, EA, Cooke, ID   +5 more
openaire   +2 more sources

Proliferation of granulosa cells in FST288-treated ovaries.

, 2015
Ovaries at 17.5 dpc were cultured alone (as a control) or with 500 ng/mL FST288 for BrdU incorporation assays. After 4 days of culture, when compared to granulosa cells of control ovaries (A-C, arrows; BrdU-positive granulosa cells), BrdU incorporation ...
Wanbao Niu (147655), Zhengpin Wang (147664), Guoliang Xia (136298), Jia Wen (431768), Zhen Teng (754980), Yijing Wang (227101), Chao Wang (146527)   +6 more
core   +1 more source

Approaches for in vitro culture of granulosa cells and ovarian follicles

, 2022
The in vitro culture of ovarian follicles or cumulus-oocyte complexes (COC) is used to study the factors that regulate follicular development and may have potential use in artificial reproductive technology (ART). Before ovulation, the follicle is formed
Andrade Amorim, Christiani, Mozdziak, Paul, Krajnik, Kornelia, Zgórecka, Wiktoria, Skowroński, Mariusz T., Kranc, Wiesława, Prochazka, Radek, Jeseta, Michal, Pieńskowski, Wojciech, Wiktoria Zgórecka, Michal Jeseta, Christiani A. Amorim, Kornelia Krajnik, Mariusz T. Skowroński, Wiesława Kranc, Radek Prochazka, Paul Mozdziak, Wojciech Pieńskowski   +17 more
core   +1 more source