Results 111 to 120 of about 284,481 (355)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Ovarian germ cell tumors in children and adolescents (literature review)

open access: yesОпухоли женской репродуктивной системы
Ovarian germ cell tumors account for 30 % of germ cell tumors of other localizations and 70 % of all ovarian neoplasms. The aim of this review is to study and systematize clinical manifestations, diagnosis and treatment of ovarian germ cell tumors in ...
E. V. Sibirskaya, Yu. E. Shaykhrazieva
doaj   +1 more source

Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study

open access: yesBMC Cancer, 2018
Background Prior small studies have shown increased expression of sperm protein 17 (Sp17) in epithelial ovarian cancer (EOC) tissue and suggest Sp17 as a potential biomarker for EOC. However, how Sp17 expression varies with histology, grade, and stage of
Laurie L. Brunette   +11 more
doaj   +1 more source

Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]

open access: yes, 2011
Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core   +2 more sources

Ovarian sclerosing stromal tumor - benign neoplasm of the young. A case study with literature review

open access: diamond, 2023
Jakub Grzybowski   +10 more
openalex   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

The clinical and morphological features of ovarian steroid cell tumors

open access: yesОпухоли женской репродуктивной системы, 2014
Ovarian steroid cell tumors are rare, unusual neoplasms. There is now no unified management tactics for patients with this pathology. The paper reviews the literature on the clinical and morphological characteristics, prognostic factors, diagnosis, and ...
E. V. Cherepanova   +3 more
doaj   +1 more source

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