Results 81 to 90 of about 928,232 (390)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

COMPARATIVE EFFECTIVENESS OF MODERN METHODS OF DIFFERENTIAL DIAGNOSIS OF OVARIAN NEOPLASMS

Мать и дитя в Кузбассе, 2018
The aim of the research – to identify the most informative methods of differential diagnosis of ovarian neoplasms at the preoperative stage. Materials and methods. The study involved 117 patients with ovarian neoplasms.
Мария Алексеевна Егунова, Ирина Георгиевна Куценко, Алла Ивановна Дмитриева, Лидия Валентиновна Пикалова, Елена Александровна Кунгурова, Наталья Александровна Василенко   +5 more
doaj  

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J, Kato, Shumei, Kurzrock, Razelle, Lippman, Scott M   +3 more
core  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Immunohistochemistry: A diagnostic aid in differentiating primary epithelial ovarian tumors and tumors metastatic to the ovary

South Asian Journal of Cancer, 2013
Introduction: Among cancers of the female genital tract, the incidence of ovarian cancer ranks below only carcinoma of the cervix and the endometrium. Recent years have witnessed significant development in the use of immunohistochemistry in diagnostic ...
Divya Kriplani, Mandakini M Patel
doaj   +1 more source

MicroRNA expression profiles in pediatric dysembryoplastic neuroepithelial tumors. [PDF]

, 2016
© Springer Science+Business Media New York 2015Among noncoding RNAs, microRNAs (miRNAs) have been most extensively studied, and their biology has repeatedly been proven critical for central nervous system pathological conditions.
A Ranger, A Spalice, A Tessitore, B Zhang, C Wang, DK Birks, DN Louis, E Ferretti, E. Kanavakis, F Chassoux, F Ozlen, F Wang, G Cui, G Della Vittoria Scarpati, G. I. Lambrou, I Qaddoumi, J Cai, J Qiao, K Yao, K. Stefanaki, M Braoudaki, M Braoudaki, M Li, M Maschio, M Thom, M Wang, M. Braoudaki, N. Prodromou, P Zhou, R Kunder, S Lu, S Vella, S. A. Papadodima, SB Ng, TM Brinkman, X Zhang, Z Jamali   +36 more
core   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Pancreaticobiliary metastasis presenting as primary mucinous ovarian neoplasm: A systematic literature review

Gynecologic Oncology Reports, 2019
True primary mucinous ovarian carcinomas are rarer than originally thought and their clinical behavior and treatment response are different than more common epithelial ovarian carcinomas.
Sarah A. Ackroyd, Lauren Goetsch, Jennifer Brown, Karen Houck, Congli Wang, Enrique Hernandez   +5 more
doaj   +1 more source

Immunohistochemical staining of tumor necrosis factor-α and interleukin-10 in benign and malignant ovarian neoplasms

Oncology Letters, 2014
Ovarian cancer is the ninth most common malignancy and the fifth leading cause of cancer death in women in the USA. The majority of malignant tumors of the ovary are diagnosed at an advanced stage, making it the most fatal gynecological cancer.
M. Jammal, Allison Araújo DA SILVA, Agrimaldo Martins Filho, Eliângela de Castro Côbo, S. Adad, E. Murta, R. Nomelini   +6 more
semanticscholar   +1 more source

Bioinformatic Analysis for the Validation of Novel Biomarkers for Cancer Diagnosis and Drug Sensitivity [PDF]

, 2015
Background: The genetic control of tumour progression presents the opportunity for bioinformatics and gene expression data to be used as a basis for tumour grading.
Lockwood, Laura Anne Rebecca
core   +2 more sources