Results 11 to 20 of about 45,008 (286)

Protocol for ovariectomy and estradiol replacement in mice

STAR Protocols
Summary: Ovariectomy, involving the surgical removal of ovaries, and estradiol replacement facilitate the understanding of sexual dimorphism-related physiological changes, encompassing reproductive biology, metabolism, and hormone-related diseases.
María Luengo-Mateos, Antía González-Vila, Ana María Torres Caldas, Ali M. Alasaoufi, Marco González-Domínguez, Miguel López, Ismael González-García, Olga Barca-Mayo   +7 more
doaj   +2 more sources

The impact of ovariectomy on calcium homeostasis and myofilament calcium sensitivity in the aging mouse heart. [PDF]

PLoS ONE, 2013
This study determined whether deficiency of ovarian estrogen starting very early in life promoted age-associated Ca(2+) dysregulation and contractile dysfunction in isolated ventricular myocytes.
Elias Fares, W Glen Pyle, Gibanananda Ray, Robert A Rose, Eileen M Denovan-Wright, Robert P Chen, Susan E Howlett   +6 more
doaj   +2 more sources

Effects of remifemin treatment on bone integrity and remodeling in rats with ovariectomy-induced osteoporosis. [PDF]

PLoS ONE, 2013
This study aims to evaluate the effects of Remifemin (isopropanolic extract of Cimicifuga Racemosa) on postmenopausal osteoporosis. 120 female Sprague-Dawley rats were randomly assigned to four groups: sham surgery with vehicle, ovariectomy with vehicle,
Guangxia Cui, Huijie Leng, Ke Wang, Jianwei Wang, Sainan Zhu, Jing Jia, Xing Chen, Weiguang Zhang, Lihua Qin, Wenpei Bai   +9 more
doaj   +2 more sources

Considerations of Timing Post-ovariectomy in Mice and Rats in Studying Anxiety- and Depression-Like Behaviors Associated With Surgical Menopause in Women

Frontiers in Behavioral Neuroscience, 2022
Citation: Rodríguez-Landa JF (2022) Considerations of Timing Post-ovariectomy in Mice and Rats in Studying Anxietyand Depression-Like Behaviors Associated With Surgical Menopause in Women. Front. Behav. Neurosci. 16:829274. doi: 10.3389/fnbeh.2022.829274
J. Rodríguez-Landa
semanticscholar   +1 more source

Ovariectomy-Induced Hepatic Lipid and Cytochrome P450 Dysmetabolism Precedes Serum Dyslipidemia

International Journal of Molecular Sciences, 2021
Ovarian hormone deficiency leads to increased body weight, visceral adiposity, fatty liver and disorders associated with menopausal metabolic syndrome. To better understand the underlying mechanisms of these disorders in their early phases of development,
H. Malínská, M. Hüttl, D. Miklankova, J. Trnovska, I. Zapletalová, M. Poruba, I. Marková   +6 more
semanticscholar   +1 more source

Effect of Vicenin-2 on ovariectomy-induced osteoporosis in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
In worldwide, osteoporosis has become one of the severe public health distress and over 200 million people get affected by tenderness and fissure during their life period. Vicenin-2 is a naturally occurring flavonoid glycoside present in Moringa oleifera,
Zheng-ping Zhang, Qinpeng Zhao, Tuan-jiang Liu, He Zhao, Ruiguo Wang, Hui Li, Yongyuan Zhang, L. Shan, B. He, Xiao-dong Wang, Linhong Huang, D. Hao, Honghui Sun   +12 more
semanticscholar   +1 more source

Laparoscopic ovariectomy in dogs in late gestation

BMC Veterinary Research, 2019
Background Surgical sterilization of stray dogs is the most widely used technique to control stray dog population. Although ovariectomy is an effective technique for elective sterilization of female dogs, most stray dog population control programs ...
Kaustubh R. Dongaonkar, Sarita U. Gulavane, Veeraraghavan M. Chariar, Kiran R. Shelar   +3 more
doaj   +1 more source

17Beta-Estradiol Inhibits Calcium-Activated Potassium Channel Expressions in Rat Whole Bladder [PDF]

International Neurourology Journal, 2016
Purpose: To investigate the effect of estrogen on the expression of calcium-activated potassium (KCa) channels in an overactive bladder rat model. To this end, mRNA and protein levels of KCa channel subtypes in the bladder of ovariectomized rats were ...
Duk Yoon Kim, Eun Kyoung Yang
doaj   +1 more source

Estrogen Deficiency Induces Mitochondrial Damage Prior to Emergence of Cognitive Deficits in a Postmenopausal Mouse Model

Frontiers in Aging Neuroscience, 2021
Background: Estrogen deficiency contributes to the development of Alzheimer’s disease (AD) in menopausal women. In the current study, we examined the impact of estrogen deficiency on mitochondrial function and cognition using a postmenopausal mouse model.
Wei Zhao, Yue Hou, Xinxin Song, Lei Wang, Fangfang Zhang, Hanting Zhang, Haiyang Yu, Yanmeng Zhou   +7 more
doaj   +1 more source

Evaluation of Some Lipid and Hematological Parameters of Blood Plasma in Ovariectomized Rats after Eight Weeks of Aerobic Exercise

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022
Background and Objective: Due to the physiological changes caused by estrogen deficiency in menopause and due to the importance of aerobic exercise as one of the non-pharmacological strategies to improve these changes, the present study was performed to ...
M Emamian Rostami, R Fathi, Kh Nasiri
doaj