Results 11 to 20 of about 25,460 (223)

Overactive bladder – 18 years – Part II [PDF]

International Brazilian Journal of Urology, 2016
Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes,
Jose Carlos Truzzi, Cristiano Mendes Gomes, Carlos A. Bezerra, Ivan Mauricio Plata, Jose Campos, Gustavo Luis Garrido, Fernando G. Almeida, Marcio Augusto Averbeck, Alexandre Fornari, Anibal Salazar, Arturo Dell’Oro, Caio Cintra, Carlos Alberto Ricetto Sacomani, Juan Pablo Tapia, Eduardo Brambila, Emilio Miguel Longo, Flavio Trigo Rocha, Francisco Coutinho, Gabriel Favre, José Antonio Garcia, Juan Castaño, Miguel Reyes, Rodrigo Eugenio Leyton, Ruiter Silva Ferreira, Sergio Duran, Vanda López, Ricardo Reges   +26 more
doaj   +2 more sources

Detrusor Arreflexia as an End Stage of Neurogenic Bladder in HAM/TSP? [PDF]

Case Reports in Medicine, 2011
The HTLV-1 virus is a known agent involved in the development of HAM/TSP. Past studies have typically observed patients with autonomic dysfunction consisting of detrusor overactivity and detrusor-sphincter dyssynergia, with the occasional observation of
Matheus Tannus, Davi Tanajura, Michael A. Sundberg, Paulo Oliveira, Neviton Castro, André Muniz Santos   +5 more
doaj   +2 more sources

The Modulation Of Detrusor Contractility By Agents Influencing Ion Channel Activity

European Pharmaceutical Journal, 2018
Background: This study specified the role of several significant ion channels regulating the metabolism of calcium ions in contraction and relaxation of human detrusor muscle in order to identify possible target for future drugs that are capable of ...
Kocmálová M., Ľupták J., Barboríková J., Kazimierová I., Grendár M., Šutovský J.   +5 more
doaj   +2 more sources

Lower Urinary Tract Symptoms as Diagnostic Clues in Parkinsonism: A Practical Framework for Neurologists. [PDF]

Mov Disord Clin Pract
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Anis S, Anis O, Lenka A, Siddiqui JH.
europepmc   +2 more sources

Botulinum toxin-A for the treatment of overactive bladder: UK contributions [PDF]

, 2013
Background: Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactivebladder (OAB) and recognised in many incontinence guidelines and pathways.
Fowler, CJ, Panicker, J. N., Fowler, C. J., Dowson, C, Khan, MS, Seth, JH, Dasgupta, P, Dasgupta, P., Panicker, JN, Sahai, A, Dowson, C., Seth, J. H., Khan, M. S., Sahai, Arun   +13 more
core   +1 more source

Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome [PDF]

, 2010
Objective: The aim of the study was a prospective assessment of patient-reported side effects in an open-label study after intradetrusor botulinum toxin injections for idiopathic overactive bladder (OAB). Patients and Methods: Botulinum toxin A injection
Mayer, Margit E., Yasmin Hocaoglu, Alexander Buchner, Hocaoglu, Yasmin, Buchner, Alexander, Christian G. Stief, Bauer, Ricarda M., Alexander Roosen, Stief, Christian G., May, Florian, Christian Gratzke, Ricarda M. Bauer, Margit E. Mayer, Gratzke, Christian, Florian May, Roosen, Alexander   +15 more
core   +1 more source

Tadalafil ameliorates bladder overactivity by restoring insulin-activated detrusor relaxation via the bladder mucosal IRS/PI3K/AKT/eNOS pathway in fructose-fed rats

Scientific Reports, 2021
The pathophysiologies of metabolic syndrome (MS) and overactive bladder (OAB) might overlap. Using fructose-fed rats (FFRs) as a rodent model of MS we investigated the effects of tadalafil (a phosphodiesterase type 5 inhibitor) on the dysregulated ...
Wei-Chia Lee, Steve Leu, Kay L. H. Wu, You-Lin Tain, Yao-Chi Chuang, Julie Y. H. Chan   +5 more
doaj   +1 more source

Urinary ATP may be a dynamic biomarker of detrusor overactivity in women with overactive bladder syndrome. [PDF]

PLoS ONE, 2013
BACKGROUND: Nowadays, there is a considerable bulk of evidence showing that ATP has a prominent role in the regulation of human urinary bladder function and in the pathophysiology of detrusor overactivity.
Miguel Silva-Ramos, Isabel Silva, Olga Oliveira, Sónia Ferreira, Maria Júlia Reis, José Carlos Oliveira, Paulo Correia-de-Sá   +6 more
doaj   +1 more source

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers-Danlos Syndrome. [PDF]

Neurourol Urodyn
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Ansari M, Pine M, Sapkalova V, Brodowsky EC, Powell CR, Burns RT.   +5 more
europepmc   +2 more sources

Detrusor wall thickness as a test for detrusor overactivity in women [PDF]

Ultrasound in Obstetrics & Gynecology, 2008
AbstractObjectiveThe measurement of detrusor wall thickness has been used as a screening test for detrusor overactivity and bladder outlet obstruction in men and women. The aim of this study was to determine, using receiver–operating characteristics (ROC) analysis, the diagnostic value of detrusor wall thickness in predicting detrusor overactivity in ...
O, Lekskulchai, H P, Dietz
openaire   +2 more sources