Results 41 to 50 of about 368,323 (315)
Propulsion and Power Research, 2021 Experiments were carried out to study the effects of compound angle, hole arrangement, and blowing ratio on the film cooling performance of multiple rows of holes on the suction surface of a turbine blade.
Zhiyu Zhou +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Numerical Computation and Optimization of Turbine Blade Film Cooling
Advances in Mechanical Engineering, 2014 The effect of film cooling parameters on the cooling effectiveness of an actual turbine blade is studied numerically. Film cooling parameters such as the hole shape, holes distribution, blowing ratio, streamwise angle, and spanwise angle are investigated
Ahmed M. Elsayed +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Energies, 2023 Several studies have previously been conducted to improve the cooling performance of film cooling. However, most of the research has conducted experiments with film cooling holes on flat plates, and thus, the results of these studies do not encompass the
Seokmin Kim +3 more
doaj +1 more source
, 2017 Most of the optimization researches on film cooling have dealt with adiabatic film cooling effectiveness on the surface. However, the information on the overall cooling effectiveness is required to estimate exact performance of the optimization ...
Bong Jun Cha +3 more
core +1 more source
Study of double-wall effusion cooling scheme for gas turbine blade applications
, 2020 Porous multi-wall cooling schemes such as double-wall cooling combined with effusion cooling offer a practical approximation to transpiration cooling which in turn present a potential for high cooling effectiveness.
Ngetich, Gladys Chepkirui
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
International Journal of Aerospace Engineering, 2013 Film cooling is vital to gas turbine blades to protect them from high temperatures and hence high thermal stresses. In the current work, optimization of film cooling parameters on a flat plate is investigated numerically.
Ahmed M. Elsayed +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source