Results 41 to 50 of about 6,718,193 (287)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Methodology and theory evaluation of overall equipment effectiveness based on market
Purpose - Continuous manufacturing systems used within the steel industry involve different machines and processes that are arranged in a sequence of operations in order to manufacture the products.
Anvari, Farhad +6 more
core +1 more source
Numerical Computation and Optimization of Turbine Blade Film Cooling
The effect of film cooling parameters on the cooling effectiveness of an actual turbine blade is studied numerically. Film cooling parameters such as the hole shape, holes distribution, blowing ratio, streamwise angle, and spanwise angle are investigated
Ahmed M. Elsayed +2 more
doaj +1 more source
The Effect of Using Ramps with Trench Cylindrical Holes on Film Cooling Effectiveness
The effect of introducing ramp with a cylindrical slot hole on the film cooling effectiveness has been investigated experimentally and numerically. The film cooling effectiveness measurements are obtained experimentally.
Ahmed A. Imram +2 more
doaj +1 more source
Several studies have previously been conducted to improve the cooling performance of film cooling. However, most of the research has conducted experiments with film cooling holes on flat plates, and thus, the results of these studies do not encompass the
Seokmin Kim +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
van den Hurk, Corina J. +6 more
core +1 more source
Study of overall cooling effectiveness of discrete holes with different angles to concave wall
Overall cooling effectiveness of curved walls with discrete angled holes has been studied in the paper through approximate simulation employing experimental concave walls with a constant curvature, which were applied intensively in the curved duct for ...
Lin, Yu-zhen +3 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Turbine cooling and heat transfer modelling for gas turbine performance simulation [PDF]
The successful design of cooling systems for gas turbine engines is a key factor to feasibility of new projects, as the trend for increasing turbine entry temperatures implies requirements for more sophisticated cooling methods.
Apostolidis, Asteris
core +5 more sources

