Results 51 to 60 of about 368,323 (315)
Case Studies in Thermal EngineeringDouble-wall structures show high effectiveness in cooling of turbine vanes and blades. Accurate prediction of the overall cooling effectiveness is important for the design of double-wall structures.
Shishu Wang +3 more
doaj +1 more source
Experimental Study of Two Rows Hybrid Film Cooling Holes Over Flat Plate Surface Using IR Technology
Journal of Techniques, 2023 The study examines the effectiveness of two rows of hybrid film cooling holes over a plate surface using infrared technology and a thermal wind tunnel.
Ahmed A. Naji +3 more
doaj +1 more source
Entropy, 2023 In the theoretical treatment of crystallization, it is commonly assumed that the relaxation processes of a liquid proceed quickly as compared to crystal nucleation and growth processes. Actually, it is supposed that a liquid is always located in the metastable state corresponding to the current values of pressure and temperature.
Jürn W. P. Schmelzer +2 more
openaire +3 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
, 2019 Excerpt: Gas turbine components are protected via a coolant that travels through internal passageways before being ejected as external film cooling. Modern computational approaches facilitate the simulation of the conjugate heat transfer that takes place
Rutledge, James L. +3 more
core +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Analysis and optimization of film cooling effectiveness [PDF]
, 2013 In the first part, an optimization strategy is described that combines high-fidelity simu- lations with response surface construction, and is applied to pulsed film cooling for turbine blades.
Babaee, Hessam
core +1 more source