Alcohol consumption and mortality from all causes, coronary heart disease, and stroke: results from a prospective cohort study of Scottish men with 21 years of follow up [PDF]
Objectives: To relate alcohol consumption to mortality. Design: Prospective cohort study. Setting: 27 workplaces in the west of Scotland. Participants: 5766 men aged 35-64 when screened in 1970-3 who answered questions on their usual weekly alcohol
Hole, D.J. +3 more
core +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Protected areas reduce poaching but not overall anthropogenic mortality of North American mammals
Protected areas are established for diverse conservation strategies, but their effectiveness for conserving species varies widely. We compiled studies that used telemetry to determine cause-specific mortality of North American mammals and compared ...
Jacob E. Hill +2 more
doaj +1 more source
Overall and cause-specific mortality in a cohort of farmers and their spouses
ObjectivesLower mortality rates compared with the general population have been reported for Agricultural Health Study (AHS) participants (enrolled 1993–1997) followed through 2007. We extended analysis of mortality among AHS participants (51 502 private pesticide applicators, their 31 867 spouses and 4677 commercial pesticide applicators from North ...
Srishti Shrestha +11 more
openaire +3 more sources
Canterbury Couples Observation Study, 2004 (REACH 01)
62 romantic couples (N = 124) from Christchurch, New Zealand participated in a behavioral observation study examining (1) conflict and problem resolution, and (2) support and relationship wellbeing.
Overall, Nickola
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Preventing infant mortality in Ohio task force report : executive summary.
Title from PDF cover (viewed on May 25, 2010).; "November 2009."; Harvested from the web on 5/25 ...
core
The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI) [PDF]
BACKGROUND: Although liver function tests (LFTs) are routinely measured in primary care, raised levels in patients with no obvious liver disease may trigger a range of subsequent expensive and unnecessary management plans.
Roderick Paul +49 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Preventing infant mortality in Ohio task force report.
Title from PDF cover (viewed on May 25, 2010).; "November 2009."; Includes bibliographical references (p.
core

