Results 111 to 120 of about 1,616,124 (301)

Characterizing patterns of opioid and stimulant use by route and associations with non-fatal overdose and xylazine use in people who have injected drugs from Baltimore, MD, 2023–2024

Drug and Alcohol Dependence Reports
Background: The fourth wave of the overdose epidemic in the United States (US) is characterized by deaths involving fentanyl with stimulants. Understanding patterns of substance use as novel drugs continue to emerge is critical to inform overdose ...
Jacqueline E. Rudolph, Liz M. Martinez-Ocasio, Kenneth A. Feder, Catherine Tomko, Javier A. Cepeda, Gregory D. Kirk, Shruti H. Mehta, Danielle German, Becky L. Genberg   +8 more
doaj   +1 more source

Assessing knowledge, attitudes, and barriers to opioid overdose among college students

BMC Public Health
Background College students are a key population for opioid use, misuse, and subsequent exposure to overdose events. However, their knowledge and attitudes in response to opioid overdose warrant further study. To assess this gap, we surveyed graduate and
Abass Babatunde, Amanda N. Stover, Brian Witrick, Moonseong Heo, Lior Rennert   +4 more
doaj   +1 more source

Implementation evaluation of a Massachusetts pilot program designed to reduce overdose deaths among Black and Latino men returning from incarceration

Frontiers in Public Health
Introduction and contextIn response to rising and disproportionate overdose deaths, a Massachusetts agency developed a program model (CARE) that incorporated evidence-based and evidence-informed practices to support recovery and overdose prevention for ...
Laura McElherne, Laura McElherne, Andrés Hoyos-Céspedes, Andrés Hoyos-Céspedes, Shanyin Yang, Shanyin Yang, Benjamin Goldberg, Benjamin Goldberg, Sarah Jalbert, Sarah Jalbert, Ranjani Krishnan Paradise, Ranjani Krishnan Paradise, Ranjani Krishnan Paradise   +12 more
doaj   +1 more source

Single‐Cell RNA Sequencing and Spatial Multiomics Unveil Microglia–Mural Interactions Underlying Notoginsenoside R1 Against Ischemic Stroke

iMetaMed, EarlyView.
Integrated scRNA‐seq and spatial multiomics provide single‐cell and spatial insights into the neuroprotective effects of NGR1, a clinically validated bioactive compound from Panax notoginseng. NGR1 was associated with a shift in microglial transcriptional states away from ischemia‐associated pro‐inflammatory Adam8hi microglia and toward the protective ...
Qikun Zhao, Wenbo Guo, Yanrong Zheng, Guoqian Cui, Bingjie Wan, Shuhui Deng, Hudong Bao, Xiao Tu, Shengshuang Chen, Jie Liao, Xiaohui Fan   +10 more
wiley   +1 more source

Harm reduction vending machines as safer supply-supporting infrastructure

Frontiers in Psychiatry
The increasingly unpredictable unregulated drug supply has intensified overdose morbidity and mortality and prompted growing interest in safer regulated supply as an upstream harm reduction strategy. Yet, safer supply programs cannot function effectively
Tessa Rife-Pennington, Tessa Rife-Pennington, Tessa Rife-Pennington   +2 more
doaj   +1 more source

Overdose Prevention Centers: An Essential Strategy to Address the Overdose Crisis

JAMA Network Open, 2022
Elizabeth A, Samuels, Dennis A, Bailer, Annajane, Yolken   +2 more
openaire   +2 more sources

Overdose Prevention Training [PDF]

Learning how to reverse an overdose saves lives.
Wilson-Charuk, Franny
core  

Opiate overdose. [PDF]

, 2005
Topics covered: • Some of the facts about opiate overdose • Signs and symptoms of acute narcosis (opiate overdose) • Contributing factors • Prevention and education • Inappropriate responses ...
Bolger, Anne
core  

Polydatin Alleviates APAP‐Induced Hepatotoxicity by Targeting C/EBPβ to Suppress the NLRP3 Inflammasome Signaling Pathway

iNew Medicine, EarlyView.
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang, Chen Wang, Yi Ding, Wei‐Kang Zhang, Ling Zheng, Li Yue, Lei Zhang   +6 more
wiley   +1 more source

Preventing overdoses with over‐the‐counter medicines

Medical Journal of Australia, 2023
Elizabeth E Roughead, Renly Lim
openaire   +2 more sources