Results 111 to 120 of about 36,883 (260)
Neuroprotection, EarlyView.Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher +8 more
wiley +1 more source
Neuroprotection, EarlyView.Experimental design and behavioral outcomes of bee venom treatment in a murine model of Parkinson's disease. Mice received an intrastriatal injection of 6‐OHDA into the right hemisphere to induce dopaminergic degeneration. Animals were subsequently treated with l‐DOPA/carbidopa, with or without bee venom (BV) administered intraperitoneally.
Silvia Josefina López‐Pérez +2 more
wiley +1 more source
Error Traps in Pediatric Neuromuscular Block
Pediatric Anesthesia, EarlyView.ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa +5 more
wiley +1 more source
Disrupted endocannabinoid signaling contributes to systemic inflammation in acute pancreatitis
The Journal of Pathology, EarlyView.Abstract Acute pancreatitis (AP) is an inflammatory disease that can lead to systemic complications in severe cases. The endocannabinoid system has emerged as a potential modulator of inflammation in AP. We investigated the role of the endocannabinoid 2‐arachidonoylglycerol (2‐AG) and the cannabinoid receptors CB1 and CB2 during AP.
Paula Goncalves‐Romeu +7 more
wiley +1 more source
Characterization of patients declining to participate in opioid overdose prevention clinical research in an emergency department setting. [PDF]
J Subst Use Addict TreatWard RC +11 more
europepmc +1 more source
Small, EarlyView.A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu +7 more
wiley +1 more source
Biden Administration Unveils Overdose Prevention Strategy [PDF]
JAMA Health Forum, 2021 openaire +2 more sources
Systems Research and Behavioral Science, EarlyView.ABSTRACT This paper examines how Participatory System Mapping (PSM), implemented through multiple parallel stakeholder workshops, can uncover interacting factors and feedback structures shaping ditch biodiversity, stimulate systemic learning and generate actionable insights for biodiversity governance.
Wouter Spekkink +3 more
wiley +1 more source
A community-based systematic review of economic evaluations of overdose prevention sites for people who use drugs: a study protocol. [PDF]
Subst Abuse Treat Prev PolicyJozaghi E +1 more
europepmc +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source