Results 91 to 100 of about 1,203,145 (219)

Overexpression of RNases does not compensate for loss of Tsn1 or Dcr1 function.

, 2022
(A) RT-qPCR analysis of expression of rnh1+ in distinct strains. pREP3X is the empty vector control. Normalization was carried out against act1+ levels. Error bars represent standard deviation (triplicate biological repeats).
Hanadi A. S. Alahamadi (12890270), Ahad A. A. Alsaiari (12890267), Ramsay J. McFarlane (12890291), Hussam A. E. Althagafi (12890279), Ellen Vernon (12890276), David W. Pryce (12890285), Othman Alzahrani (12890273), Natalia Gomez-Escobar (7831), Jane A. Wakeman (12890288), Nasser S. Almobadel (12890282)   +9 more
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Tuning Escherichia coli for membrane protein overexpression [PDF]

, 2008
A simple generic method for optimizing membrane protein overexpression in Escherichia coli is still lacking. We have studied the physiological response of the widely used ‘‘Walker strains’’ C41(DE3) and C43(DE3), which are derived from BL21(DE3), to ...
Schlegel, Susan,, Appel, Ansgar, Draheim, Roger, van Wijk, Klaas J., Tarry, Michael,, Persson, Jan O., de Gier, Jan-Willem, Klepsch, Mirjam M., Tarry, Michael, Persson, Jan O.,, Hogbom, Martin, Wagner, Samuel, Draheim, Roger,, Appel, Ansgar,, Klepsch, Mirjam M.,, Slotboom, Dirk J., Wagner, Samuel,, Schlegel, Susan, de Gier, Jan-Willem,, Högbom, Martin,   +19 more
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The role of overexpressed HER2 in transformation

Annals of Oncology, 2001
The HER family of receptors has an important role in the network of cell signals controlling cell growth and differentiation. Although the activity of the HER receptor is strictly controlled in normal cells, HER2 receptor overexpression plays a pivotal role in transformation and tumorigenesis.
Neve RM, Lane HA, Hynes NE
openaire   +3 more sources

Overexpression Study

, 2017
Overexpression ...
Schroedel, Randi, Vatistas, Nikki, Berube, Erin   +2 more
core  

miR-330 overexpression does not alter chemosensitivity.

, 2015
The clonogenic survival assay was used to assess alterations in cellular sensitivity to cisplatin and 5-FU with miR-330 overexpression. The approximate IC50 doses of cisplatin and 5-FU were used to treat the cells for 24 h.
John V. Reynolds (589295), Becky A. S. Bibby (776954), Stephen G. Maher (589292)   +2 more
core   +1 more source

Maternal-effect embryonic lethality accompanying HeT-A overexpression.

, 2021
Maternal-effect embryonic lethality accompanying HeT-A overexpression.
Valeriya Morgunova (3965825), Elena A. Mikhaleva (11539771), Maria Kordyukova (5698190), Ivan Butenko (3455030), Olga V. Pobeguts (8497305), Alla Kalmykova (586297)   +5 more
core   +1 more source

Overexpression of LpxK increases LpxC concentration.

, 2015
(A) Lower row shows LpxK bands on an SDS-PAGE gel, arising from overexpression induced with the amount of IPTG shown at the top of each column. The upper row shows the resultant LpxC bands on a Western blot for the same induction levels.
Akintunde Emiola (731249), Steven S. Andrews (251777), John George (731250)   +2 more
core   +1 more source

SnoN Overexpression Overcomes TGF-β1 Inhibition.

, 2013
(A) Neurite outgrowth in primary adult DRG neurons in the presence of TGF-β1. Cells expressing GFP and NF200 (shown) are quantified. (B) Overexpression of SnoN in neurons appears to increase neurite length even in presence of TGF-β1, quantified in D. (C)
Azad Bonni (221908), Mark H. Tuszynski (440974), Jiun L. Do (440973)   +2 more
core   +1 more source

MEKi-mediated ERα overexpression is independent of erbB activity but MAPK-dependent.

, 2013
(A) The ERα antagonist fulvestrant prevents MEKi-mediated ERα overexpression, and partially suppresses the phosphorylation of erbB2 and EGFR by MEKi. (B) Overexpression of ERα by MEKi is erbB-independent, since the pan-erbB inhibitor lapatinib (erbBi ...
Susan Band Horwitz (279124), Hayley M. McDaid (279125), June Y. Hou (279120), Leleesha Samaweera (279122), Rachel Hazan (171509), Alicia Rodriguez-Gabin (279121), Gary L. Goldberg (279123)   +6 more
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Skeletal muscle-specific overexpression of SIRT1 does not enhance whole-body energy expenditure or insulin sensitivity in young mice [PDF]

, 2013
Aims/hypothesis: The NAD+-dependent protein deacetylase sirtuin (SIRT)1 is thought to be a key regulator of skeletal muscle metabolism. However, its precise role in the regulation of insulin sensitivity is unclear. Accordingly, we sought to determine the
White, Amanda T, Hamilton, David Lee, McCurdy, Carrie E, Philp, Andrew, Schenk, Simon, Johnson, Casey D   +5 more
core   +1 more source