Results 101 to 110 of about 1,203,145 (219)
Quantitative nature of overexpression experiments
Molecular Biology of the Cell, 2015 Overexpression experiments are sometimes considered as qualitative experiments designed to identify novel proteins and study their function. However, in order to draw conclusions regarding protein overexpression through association analyses using large-scale biological data sets, we need to recognize the quantitative nature of overexpression ...
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Nab4 Overexpression Affects SUA7 Cleavage Site Selection
, 2013 Shown is the 3′ RACE analysis of the SUA7 transcript during a time course of Nab4 overexpression. Nab4 overexpression was driven by a galactose-inducible promoter. This strain was compared to a vector-only control, induced in parallel.
Christine Guthrie (115944) +2 more
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An overexpression screen for PCP defects identifies dGIPC.
, 2013 A. Schematic of the overexpression screen. Males from EP collections were mated with females expressing the Gal4 transcription factor in the apterous domain (dorsal notum and wing). B–C. Overexpression of the EP line GS2053 gives PCP defects in the notum
Alexandre Djiane (363866) +1 more
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Mapping pathways and phenotypes by systematic gene overexpression
, 2006 Many disease states result from gene overexpression, often in a specific genetic context. To explore gene overexpression phenotypes systematically, we assembled an array of 5280 yeast strains, each containing an inducible copy of an S.
Nicolle Preston +23 more
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Overexpression of human SOD1 improves survival of mice susceptible to endotoxic shock
, 2012 Jean Charchaflieh,1,2 Georges I Labaze,1 Pulsar Li,1 Holly Van Remmen,3 Haekyung Lee,1 Helen Stutz,1 Arlan Richardson,3 Asher Emanuel,1 Ming Zhang1,41Department of Anesthesiology, State University of New York (SUNY) Downstate Medical Center, New York, NY,
Richardson A +8 more
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Overexpression of ACLY and ME in correlation with patient’s overall survival.
, 2015 A) Overexpression of ACLY is associated with a better outcome in young patients but not in older patients. B) ME overexpression shows a statistical trend towards a poorer overall survival in older patients.
Antje Prasse (354621) +10 more
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, 2019 Qianqian Zhou,1,* Chao Song,1,* Xiaoqiu Liu,2,3,* Hao Qin,1 Lixia Miao,1 Xuesen Zhang1 1State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China; 2Key Laboratory of Pathogen Biology of Jiangsu Province, Nanjing Medical ...
Liu X +5 more
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Ntag degradation is enhanced by ClpP and ClpS overexpression.
, 2016 Overexpression of a perturbation protein was used to test for degradation effects on Ntag-RFP. Overall degradation is reduced with the target/perturbation plasmid system as indicated by the control conditions (ΔclpP + pTrc versus WT + pTrc).
John W. Bostick (2268028) +3 more
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Stretching Induces Overexpression of RhoA and Rac1 GTPases in Breast Cancer Cells
, 2019 Rho GTPases are well known for regulating cell morphology and intracellular interactions. They can either be oncogenic or tumor suppressors. However, these proteins are associated with the acquirement of malignant features by cancer cells.
Barton, Matthew +5 more
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HAL2 overexpression induces iron acquisition in bdf1 Delta cells and enhances their salt resistance
, 2017 The yeast Saccharomyces cerevisiae is capable of responding to various environmental stresses, such as salt stress. Such responses require a complex network and adjustment of the gene expression network.
Fu, Jiafang +8 more
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