Results 71 to 80 of about 1,171,772 (218)

Emerging functions of RANKL in lymphoid tissues

Frontiers in Immunology, 2012
The tumor necrosis factor superfamily (TNFSF) members play pivotal roles in embryonic development of lymphoid tissue and in their homeostasis. RANKL (Receptor activator of NF-kappaB ligand, also called TRANCE, TNFSF11) is recognized as an important ...
Christopher G Mueller, Estelle eHess, Estelle eHess   +2 more
doaj   +1 more source

Interpretation of overexpression profiling.

, 2023
A) GOFAs manifest the potential for cellular stress tolerance (ideal state) due to compensating for cellular requirements. GOFA improves cellular fitness by supplementing elements (an arrow indicates) that are deficient compared to the ideal cellular ...
Mami Yoshimura (5909048), Hisao Moriya (63197), Charles Boone (21213), Shuji Shigenobu (464699), Nozomu Saeki (15374719), Yuichi Eguchi (15374722), Yoko Yashiroda (2270305), Takayuki Sekito (755779), Chie Yamamoto (1816267)   +8 more
core   +1 more source

Functional Characterization of a Putative Glycine max ELF4 in Transgenic Arabidopsis and Its Role during Flowering Control

Frontiers in Plant Science, 2017
Flowering is an important trait in major crops like soybean due to its direct relation to grain production. The circadian clock mediates the perception of seasonal changes in day length and temperature to modulate flowering time. The circadian clock gene
Alexandre L. Nepomuceno, Juliana Marcolino-Gomes, Thiago J. Nakayama, Hugo B. C. Molinari, Marcos F. Basso, Liliane M. M. Henning, Renata Fuganti-Pagliarini, Frank G. Harmon, Frank G. Harmon   +8 more
doaj   +1 more source

The role of overexpressed HER2 in transformation

Annals of Oncology, 2001
The HER family of receptors has an important role in the network of cell signals controlling cell growth and differentiation. Although the activity of the HER receptor is strictly controlled in normal cells, HER2 receptor overexpression plays a pivotal role in transformation and tumorigenesis.
Neve RM, Lane HA, Hynes NE
openaire   +3 more sources

Gene Expression Analyses of HER-2/neu and ESR1 in Patients with Breast Cancer

Brazilian Archives of Biology and Technology, 2017
Background: Her-2 and ESR1 genes, that interact in the cell signaling pathway, are the most important molecular markers of breast cancer, which have been amplified or overexpressed in 30% and 70%, respectively.
Omid Kheyri Nadergoli, Mohammad Ali Hosseinpour Feizi, Hossein Samadi Kafil, Nasser Pouladi, Ali Hosseinzadeh, Leila Rostamizadeh, Vahid Montazeri, Ashraf Fakhrjou, Ebrahim Sakhinia, Morteza Seifi   +9 more
doaj   +1 more source

Overexpression of an isoform of AML1 in acute leukemia and its potential role in leukemogenesis [PDF]

, 2008
AML1/RUNX1 is a critical transcription factor in hematopoietic cell differentiation and proliferation. From the _AML1_ gene, at least three isoforms, _AML1a_, _AML1b_ and _AML1c_, are produced through alternative splicing.
Zhen Tian, Haiyan Xing, Xiangrong Liu, Dong-er Zhang, Min Wang, Qing Zhang, Qing Rao, Jianxiang Wang, Chunlin Zhou   +8 more
core  

Overexpression of Cdc20 Leads to Impairment of the Spindle Assembly Checkpoint and Aneuploidization in Oral Cancer

, 2007
Defects in the spindle assembly checkpoint are thought to be responsible for an increased rate of aneuploidization during tumorigenesis. Despite a plethora of information on the correlation between BUB-MAD gene expression levels and defects in the ...
Mondal, Gourish, Sengupta, Shiladitya, Saunders, William S, Gollin, Susanne M, Gollin, Susanne M., Panda, Chinmay Kumar, Saunders, William S., Roychoudhury, Susanta, Panda, Chinmoy K.   +8 more
core   +1 more source

Overexpression of human SOD1 improves survival of mice susceptible to endotoxic shock

, 2012
Jean Charchaflieh,1,2 Georges I Labaze,1 Pulsar Li,1 Holly Van Remmen,3 Haekyung Lee,1 Helen Stutz,1 Arlan Richardson,3 Asher Emanuel,1 Ming Zhang1,41Department of Anesthesiology, State University of New York (SUNY) Downstate Medical Center, New York, NY,
Richardson A, Labaze GI, Van Remmen H, Li P, Lee H, Zhang M, Charchaflieh J, Emanuel A, Stutz H   +8 more
core  

Verification of circMORC3 overexpression plasmid.

, 2023
(A) Sanger sequencing validation of circMORC3, Flag-circMORC3, and Flag-circMORC3-ATG-mut overexpression plasmid capable of producing circular circMORC3.
Weiwei Zheng (140828), Linchao Wang (17706020), Tianjun Xu (138445), Yanhong Song (4516555), Xing Lv (277606)   +4 more
core   +1 more source

Overexpression of the Mas1 gene mitigated LPS-induced inflammatory injury in mammary epithelial cells by inhibiting the NF-κB/MAPKs signaling pathways

Frontiers in Veterinary Science
Breast infection is the primary etiology of mastitis in dairy cows, leading to a reduction in the quality of dairy products and resulting in substantial economic losses for animal husbandry.
Shuping Yan, Xianghong Ju, Xianghong Ju, Jianlong Lao, Zhaohai Wen, Yanhong Yong, Yin Li, Youquan Li   +7 more
doaj   +1 more source