Results 51 to 60 of about 1,171,772 (218)

Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice

, 2023
BACKGROUND: αB-Crystallin is a heat shock chaperone protein which binds to misfolded proteins to prevent their aggregation. It is overexpressed in a wide-variety of cancers.
Apaja, Pirjo M., Sharma, Sowmya, Bain, Amanda Louise, Behnam Rashidieh, Duijf, Pascal H.G., John Finnie, Stewart, Cameron Allan, Pascal H. G. Duijf, Pirjo M. Apaja, Sowmya Sharma, Khanna, Kum Kum, Duijf, Pascal H. G., Simon Manuel Tria, Cameron Allan Stewart, Jacinta Ley Simmons, Apaja, Pirjo M, Duijf, Pascal HG, Simmons, Jacinta Ley, Rashidieh, Behnam, Finnie, John, Kum Kum Khanna, Amanda Louise Bain, https://orcid.org/, Tria, Simon Manuel   +23 more
core   +1 more source

Functional Verification of Differentially Expressed Genes Following DENV2 Infection in Aedes aegypti

Viruses
The dengue virus (DENV) is primarily transmitted by Aedes aegypti. Investigating genes associated with mosquito susceptibility to DENV2 offers a theoretical foundation for targeted interventions to regulate or block viral replication and transmission ...
Xiaoli Chen, Xinyu Zhou, Xiaoxue Xie, Bo Li, Teng Zhao, Haotian Yu, Dan Xing, Jiahong Wu, Chunxiao Li   +8 more
doaj   +1 more source

In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis

, 2016
Cell cycle genes are often aberrantly expressed in cancer, but how their misexpression drives tumorigenesis mostly remains unclear. From S phase to early mitosis, EMI1 (also known as FBXO5) inhibits the anaphase-promoting complex/cyclosome, which ...
Cato, K, Pavey, S., Gabrielli, BG, Duijf, PHG, Vaidyanathan, S, Tang, L., Haass, NK, Vaidyanathan, S., Duijf, P.H.G., Pavey, S, Haass, N.K., Gabrielli, B.G., Tang, L, Cato, K.   +13 more
core   +1 more source

Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes [PDF]

, 2012
mRNA levels of the urokinase receptor splice variant uPAR-del4/5 are associated with prognosis in breast cancer. Its overexpression in cancer cells affects tumor biologically relevant processes.
Sato, Sumito, Soelch, Susanne, Luther, Thomas, Schmitt, Manfred, Baretton, Gustavo, Grismayer, Bettina, Kopitz, Charlotte, Krueger, Achim, Kotzsch, Matthias, Ries, Christian, Magdolen, Viktor, Grismayer, B;Sato, S;Kopitz, C;Ries, C;Soelch, S;Schmitt, M;Baretton, G;Kruger, A;Luther, T;Kotzsch, M;Magdolen, V   +11 more
core   +1 more source

Expression, Purification and Characterization of a Novel Rusticyanin from the Psychrotolerant Acidithiobacillus ferrivorans

Separations, 2023
Rusticyanin plays a crucial role in ferrous oxidation of sulfide minerals during bioleaching for industrial metal extraction. Diverse isoforms of rusticyanin have been found, but until now, except for type-A rusticyanin, other isoforms or sources of ...
Yuandong Liu, Lixiang Chen, Xiangdong Shangguan, Jingying Ouyang, Jiayu He, Kan Wang, Yan Tong, Runlan Yu, Weimin Zeng, Xueling Wu, Li Shen, Guanzhou Qiu   +11 more
doaj   +1 more source

Overexpression of the Capebp2 Gene Encoding the PEBP-like Protein Promotes the Cap Redifferentiation in Cyclocybe aegerita

Journal of Fungi, 2023
Phosphatidylethanolamine-binding protein (PEBP) is widely involved in various physiological behaviors, such as the transition from vegetative growth to reproductive growth in plants, tumorigenesis in the human, etc.
Bopu Cheng, Nan Tao, Yuanhao Ma, Hongmei Chai, Ping Liu, Weimin Chen, Yongchang Zhao   +6 more
doaj   +1 more source

MicroRNA and HER2-overexpressing Cancer [PDF]

MicroRNA, 2013
The discovery of microRNAs (miRNAs) has opened up new avenues for studying cancer at the molecular level, featuring a post-genomic era of biomedical research. These non-coding regulatory RNA molecules of ~22 nucleotides have emerged as important cancer biomarkers, effectors, and targets.
Wang, Shizhen Emily, Lin, Ren-Jang
openaire   +2 more sources

Expression Analysis and Interaction Protein Screening of CoZTL in Camellia oleifera Abel

Horticulturae, 2023
Camellia oleifera Abel., which produces fruits of high comprehensive utilization value, is an important woody oil tree in China. ZEITLUPE (ZTL) is a blue light receptor and clock component protein that is involved in various physiological and biochemical
Shuangshuang Ren, Lemei Juan, Jiacheng He, Qian Liu, Jindong Yan, Jian’an Li   +5 more
doaj   +1 more source

SURVIVAL CURVE ANALYSIS FOR DROSOPHILA MELANOGASTER WITH D-GADD45 OVEREXPRESSION IN THE NERVOUS SYSTEM

Вавиловский журнал генетики и селекции, 2015
Overexpression of the Gadd45 gene in the nervous system of Drosophila melanogaster increases the life span. We have performed the Gompertz approximation of the survival curve and revealed a life span increase as a result of decrease of the R parameter ...
E. N. Plyusnina, M. V. Shaposhnikov, E. N. Andreeva, A. A. Moskalev, L. V. Omelyanchuk   +4 more
doaj  

Reproducibility of overexpression profiling.

, 2023
Overexpression can help life adapt to stressful environments, making an examination of overexpressed genes valuable for understanding stress tolerance mechanisms.
Mami Yoshimura (5909048), Hisao Moriya (63197), Charles Boone (21213), Shuji Shigenobu (464699), Nozomu Saeki (15374719), Yuichi Eguchi (15374722), Yoko Yashiroda (2270305), Takayuki Sekito (755779), Chie Yamamoto (1816267)   +8 more
core   +1 more source