Results 31 to 40 of about 1,435,507 (315)
, 2022 reservedMicroalgae have become highly interesting organisms for biotechnological use due to a range of conveniences including their high photosynthetic efficiency or the possibility to be used as “green” biofactories that generate molecules of our ...
DANEI, MARCO
core
, 2022 One of the important armories that plant pathogens utilize to successfully colonize the plants are small secreted effector proteins, which could perform a variety of functions from suppression of plant innate immunity to manipulation of plant physiology ...
Kanyuka, K.
core +1 more source
Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential
ACS Chemical Biology, 2019 Many anticancer strategies rely on the promotion of apoptosis in cancer cells as a means to shrink tumors. Crucial for apoptotic function are executioner caspases, most notably caspase-3, that proteolyze a variety of proteins, inducing cell death ...
Matthew W. Boudreau +2 more
semanticscholar +1 more source
The Role of Neurotransmitters in Protection against Amyloid- β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons. [PDF]
, 2013 Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide.
Chilumuri, Amrutha +5 more
core +1 more source
Plk1 overexpression induces chromosomal instability and suppresses tumor development
Nature Communications, 2018 Polo-like kinase 1 (Plk1) is overexpressed in a wide spectrum of human tumors, being frequently considered as an oncogene and an attractive cancer target. However, its contribution to tumor development is unclear.
G. de Cárcer +12 more
semanticscholar +1 more source
c‐MET Overexpression in Colorectal Cancer: A Poor Prognostic Factor for Survival
Clinical colorectal cancer, 2018 Micro‐Abstract: Mesenchymal‐epithelial transition factor gene (c‐MET) overexpression might be an important biomarker in colorectal cancer (CRC). We evaluated the incidence of c‐MET overexpression and its prognostic significance in 255 patients with ...
Su Jin Lee +7 more
semanticscholar +1 more source
, 2014 Oxidative folding of secretory proteins in the endoplasmic reticulum (ER) is a redox active process, which also impacts the redox conditions in the cytosol. As the transcription factor Yap1 is involved in the transcriptional response to oxidative stress,
Stephan Hann +6 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications
Genes & cancer, 2015 Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Anna Shvartsur, B. Bonavida
semanticscholar +1 more source