Results 31 to 40 of about 1,507,610 (341)

Quantifying the benefit of a proteome reserve in fluctuating environments. [PDF]

, 2017
The overexpression of proteins is a major burden for fast-growing bacteria. Paradoxically, recent characterization of the proteome of Escherichia coli found many proteins expressed in excess of what appears to be optimal for exponential growth.
Erickson, David W, Gerland, Ulrich, Hwa, Terence, Mori, Matteo, Schink, Severin   +4 more
core   +3 more sources

Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans

Diagnostics, 2020
Mucopolysaccharidosis type II (MPS II) is an X-linked disorder resulting from a deficiency in iduronate 2-sulfatase (IDS), which is reported to be caused by gene mutations in the iduronate 2-sulfatase (IDS) gene.
Cheng-Yung Lin, Hsiang-Yu Lin, Chih-Kuang Chuang, Po-Hsiang Zhang, Ru-Yi Tu, Shuan-Pei Lin, Huai-Jen Tsai   +6 more
doaj   +1 more source

Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]

, 2009
Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Jones, E. A., Naylor, Richard William
core   +1 more source

Research Note: SOCS2 contributes to reduction of the third digit during development of the chicken forelimb

Poultry Science
: The development of the avian wing pattern has been the subject of heated debate due to its special shape. The Suppressor of cytokine signaling 2 (SOCS2) gene encodes a negative regulator of growth hormone (GH) signaling and bone growth and is known to ...
Xiaoping Li, Shanshan Li, Shibin Bai, Yining Tang, Ziqiu Jia, Jialong Yin, Xiaona Xu, Junpeng Zhang, David M. Irwin, Shuyi Zhang, Zhe Wang   +10 more
doaj   +1 more source

Functional Characterization of GhACX3 Gene Reveals Its Significant Role in Enhancing Drought and Salt Stress Tolerance in Cotton

Frontiers in Plant Science, 2021
The acyl-coenzyme A oxidase 3 (ACX3) gene involved in the β-oxidation pathway plays a critical role in plant growth and development as well as stress response.
Margaret L. Shiraku, Richard Odongo Magwanga, Richard Odongo Magwanga, Xiaoyan Cai, Joy Nyangasi Kirungu, Yanchao Xu, Teame Gereziher Mehari, Yuqing Hou, Yuhong Wang, Stephen Gaya Agong, Renhai Peng, Kunbo Wang, Zhongli Zhou, Fang Liu   +13 more
doaj   +1 more source

The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation. [PDF]

, 2016
Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting protein. However, its precise function in cancer remains largely uninvestigated.
Chang, Hong-Tai, Chang, Yu-Chang, Chen, Chi-Long, Ger, Luo-Ping, Hsiao, Michael, Huang, Ming-Shyan, Jan, Yi-Hua, Lai, Tsung-Ching, Lin, Tsung-Chieh, Lin, Yuan-Feng, Liu, Yu-Peng, Pan, Wen-An, Shyy, John Y-J, Su, Chia-Yi, Tsai, Ming-Daw, Wu, Pei-Yu, Yang, Chih-Jen, Yeh, Chi-Tai   +17 more
core   +2 more sources

Expression Pattern and Functional Analysis of MebHLH149 Gene in Response to Cassava Bacterial Blight

Plants
The significant reduction in cassava (Manihot esculenta Crantz) yields attributed to cassava bacterial blight (CBB) constitutes an urgent matter demanding prompt attention.
Min Cui, Feifei An, Songbi Chen, Xindao Qin   +3 more
doaj   +1 more source

Overexpression of PIF4 affects plant morphology and accelerates reproductive phase transitions in soybean

Food and Energy Security, 2021
Phytochrome‐interacting factor 4 acts as a signalling hub for integrating multiple environmental cues like light and temperature. While the function of PIF4 in the model plant Arabidopsis has been studied, there is limited knowledge regarding the role of
Hina Arya, Mohan B. Singh, Prem L. Bhalla   +2 more
doaj   +1 more source

The Overexpression of an EnvZ-like Protein Improves the Symbiotic Performance of Mesorhizobia

Agronomy
The two-component signal transduction system EnvZ/OmpR is described to mediate response to osmotic stress, although it regulates genes involved in other processes such as virulence, fatty acid uptake, exopolysaccharide production, peptide transportation,
José Rodrigo da-Silva, Esther Menéndez, Solange Oliveira, Ana Alexandre   +3 more
doaj   +1 more source

Compartmentalized PDE4A5 signaling impairs hippocampal synaptic plasticity and long-term memory [PDF]

, 2016
Alterations in cAMP signaling are thought to contribute to neurocognitive and neuropsychiatric disorders. Members of the cAMP-specific phosphodiesterase 4 (PDE4) family, which contains >25 different isoforms, play a key role in determining spatial ...
Abel, Ted, Baillie, George W., Bruinenberg, Vibeke M., Guercio, Leonardo A., Hansen, Rolf T., Havekes, Robbert, Houslay, Miles D., Lee, Yool, Linton, Edward, Meerlo, Peter, Neves, Susana R., Park, Alan J., Tolentino, Rosa E., Tudor, Jennifer C.   +13 more
core   +5 more sources