Results 21 to 30 of about 1,171,772 (218)

Overexpression of DGAT2 Stimulates Lipid Droplet Formation and Triacylglycerol Accumulation in Bovine Satellite Cells

Animals, 2022
Intramuscular fat (IMF) is closely related to the tenderness, juiciness, and flavor of beef, and is an important indicator for beef quality assessment internationally.
Jun-Fang Zhang, Seong-Ho Choi, Qiang Li, Ying Wang, Bin Sun, Lin Tang, En-Ze Wang, Huan Hua, Xiang-Zi Li   +8 more
doaj   +1 more source

Endocan Overexpression in Pterygium

Cornea, 2017
Purpose: The aim of this study was to evaluate the possible role of endocan in the pathogenesis of pterygium. Methods: The study was conducted on 33 patients with primary pterygium and 20 control subjects with normal bulbar conjunctiva.
Kilic, Rasit, Kurt, Ali, Tad, Murat, Tasdemir, Sedat   +3 more
openaire   +2 more sources

Skeletal-Muscle-Specific Overexpression of Chrono Leads to Disruption of Glucose Metabolism and Exercise Capacity [PDF]

, 2022
Disruption of circadian rhythms is related to disorders of glucose metabolism, and the molecular clock also exists in skeletal muscle. The ChIP-derived repressor of network oscillator (Chrono) and brain and muscle ARNT-like 1 (Bmal1) are core circadian ...
Wei, Hao, Hao Wei, Ying Zhang, Wang, Jianxiong, Yan, Lu, Zhu, Rongxin, Zheng, Lan, Jianxiong Wang, He, Shiyi, Shiyi He, Zhang, Ying, Lan Zheng, Rongxin Zhu, Lu Yan   +13 more
core   +1 more source

Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation

, 2020
Glioblastoma multiforme (GBM) is the most common and malignant type of central nervous system tumours in adults. Strict regulation of glucose homeostasis has a significant role in GBM pathogenesis.
Gorgisen, Gökhan, Zafer Yaren, Gokhan Gorgisen, Yaren, Z   +3 more
core   +1 more source

c-erbB-2 expression in benign and malignant breast disease. [PDF]

, 1988
An antibody, 21N, raised against a synthetic peptide from the predicted sequence of the c-erbB-2 protein has been used immunocytochemically in a retrospective study of formalin fixed paraffin embedded breast biopsies.
Gusterson, BA, NM Gibbs, S Harrison, BA Gusterson, Powles, TJ, C Elliott, TJ Powles, Monaghan, P, S Ashley, Ashley, S, LG Machin, Gullick, WJ, Gibbs, NM, P Monaghan, Machin, LG, Elliott, C, Harrison, S, WJ Gullick   +17 more
core   +1 more source

miR394 Acts as a Negative Regulator of Arabidopsis Resistance to B. cinerea Infection by Targeting LCR

Frontiers in Plant Science, 2018
Gray mold of tomato is caused by the pathogen Botrytis cinerea. MicroRNAs play a crucial role in the biotic and abiotic stress responses of plants and regulate their targets by gene silencing.
Xing Tian, Liping Song, Yi Wang, Weibo Jin, Fudan Tong, Fangli Wu   +5 more
doaj   +1 more source

Perspectives on blockade of TGFβ overexpression [PDF]

Kidney International, 2006
Many approaches to blocking profibrotic TGFbeta overexpression are under way. Therapeutic targeting of TGFbeta-Smad signaling holds promise for slowing or halting progressive renal disease. In this issue, Fukasawa et al., using the unilateral ureteral obstruction model, provide a new target for therapeutic intervention by identifying loss of the Smad ...
Huang, Y., Border, W.A., Noble, N.A.
openaire   +2 more sources

The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity [PDF]

, 2012
Overexpression or mutation of alpha-Synuclein is associated with protein aggregation and interferes with a number of cellular processes, including mitochondrial integrity and function.
Butler, Erin K., Jane P Toegel, Jane P. Toegel (185544), Winklhofer Konstanze F., A Kathrin Lutz, Voigt Aaron, Falkenburger, Bjoern, Toegel Jane P., Konstanze F. Winklhofer (185550), Gerhardt, Ellen, Karsten Peter, A. Kathrin Lutz (185542), Voigt, Aaron, Butler Erin K., Toegel, Jane P., Peter Karsten (123433), Björn Falkenburger (185548), Schulz, Joerg B., Falkenburger, Bjoern H., Peter Karsten, Ellen Gerhardt (185546), Andrea Reinartz (185549), Reinartz, Andrea, Erin K Butler, Ellen Gerhardt, Lutz A. Kathrin, Jörg B Schulz, Gerhardt Ellen, Aaron Voigt (123446), Reinartz Andrea, Jörg B. Schulz (123442), Lutz, A. Kathrin, Karsten, Peter, Konstanze F Winklhofer, Aaron Voigt, Björn Falkenburger, Schulz Jörg B., Erin K. Butler (185540), Winklhofer, Konstanze F., Falkenburger Björn, Andrea Reinartz, Toegel, Jane Patricia   +41 more
core   +2 more sources

Genetic Modification of KNAT7 Transcription Factor Expression Enhances Saccharification and Reduces Recalcitrance of Woody Biomass in Poplars

Frontiers in Plant Science, 2021
The precise role of KNAT7 transcription factors (TFs) in regulating secondary cell wall (SCW) biosynthesis in poplars has remained unknown, while our understanding of KNAT7 functions in other plants is continuously evolving.
Yogesh Kumar Ahlawat, Yogesh Kumar Ahlawat, Akula Nookaraju, Anne E. Harman-Ware, Crissa Doeppke, Ajaya K. Biswal, Ajaya K. Biswal, Chandrashekhar P. Joshi   +7 more
doaj   +1 more source

Galanin overexpressing transgenic mice [PDF]

Neuropeptides, 2002
Galanin overexpressing transgenic mice (GAL-tg) were generated on two different promoters. Both lines of GAL-tg displayed high levels of galanin in the hippocampus and reduced sensitivity to seizures, as compared to their respective wildtype littermate controls (WT).
Bartfai, Tamas, Hohmann, John G., Steiner, Robert A., Xu, Zhi-Qing D., Xu, Xiao-Jun, Holmberg, Kristina, Blakeman, Karin H., Hokfelt, Tomas, Mufson, Elliott J., Crawley, Jacqueline N., Wiesenfeld-Hallin, Zsuzsanna, Teklemichael, Dawit N.   +11 more
openaire   +2 more sources