Results 41 to 50 of about 1,203,145 (219)

Galanin overexpressing transgenic mice [PDF]

Neuropeptides, 2002
Galanin overexpressing transgenic mice (GAL-tg) were generated on two different promoters. Both lines of GAL-tg displayed high levels of galanin in the hippocampus and reduced sensitivity to seizures, as compared to their respective wildtype littermate controls (WT).
Bartfai, Tamas, Hohmann, John G., Steiner, Robert A., Xu, Zhi-Qing D., Xu, Xiao-Jun, Holmberg, Kristina, Blakeman, Karin H., Hokfelt, Tomas, Mufson, Elliott J., Crawley, Jacqueline N., Wiesenfeld-Hallin, Zsuzsanna, Teklemichael, Dawit N.   +11 more
openaire   +2 more sources

Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans

Diagnostics, 2020
Mucopolysaccharidosis type II (MPS II) is an X-linked disorder resulting from a deficiency in iduronate 2-sulfatase (IDS), which is reported to be caused by gene mutations in the iduronate 2-sulfatase (IDS) gene.
Cheng-Yung Lin, Hsiang-Yu Lin, Chih-Kuang Chuang, Po-Hsiang Zhang, Ru-Yi Tu, Shuan-Pei Lin, Huai-Jen Tsai   +6 more
doaj   +1 more source

Securin is overexpressed in breast cancer [PDF]

Modern Pathology, 2005
Securin regulates sister chromatid separation during mitosis, induces bFGF-mediated angiogenesis, and securin overexpression causes in vitro transformation and in vivo tumor formation in nude mice. As estrogen administration to oophorectomized rats increased pituitary securin expression, we used immunohistochemistry to examine securin and estrogen ...
Selam, Ogbagabriel, Manory, Fernando, Frederic M, Waldman, Shikha, Bose, Anthony P, Heaney   +4 more
openaire   +2 more sources

Research Note: SOCS2 contributes to reduction of the third digit during development of the chicken forelimb

Poultry Science
: The development of the avian wing pattern has been the subject of heated debate due to its special shape. The Suppressor of cytokine signaling 2 (SOCS2) gene encodes a negative regulator of growth hormone (GH) signaling and bone growth and is known to ...
Xiaoping Li, Shanshan Li, Shibin Bai, Yining Tang, Ziqiu Jia, Jialong Yin, Xiaona Xu, Junpeng Zhang, David M. Irwin, Shuyi Zhang, Zhe Wang   +10 more
doaj   +1 more source

Functional Characterization of GhACX3 Gene Reveals Its Significant Role in Enhancing Drought and Salt Stress Tolerance in Cotton

Frontiers in Plant Science, 2021
The acyl-coenzyme A oxidase 3 (ACX3) gene involved in the β-oxidation pathway plays a critical role in plant growth and development as well as stress response.
Margaret L. Shiraku, Richard Odongo Magwanga, Richard Odongo Magwanga, Xiaoyan Cai, Joy Nyangasi Kirungu, Yanchao Xu, Teame Gereziher Mehari, Yuqing Hou, Yuhong Wang, Stephen Gaya Agong, Renhai Peng, Kunbo Wang, Zhongli Zhou, Fang Liu   +13 more
doaj   +1 more source

Testing the overexpression of a bacterial PETase using a novel overexpression system in Nannochloropsis oceanica

, 2022
reservedMicroalgae have become highly interesting organisms for biotechnological use due to a range of conveniences including their high photosynthetic efficiency or the possibility to be used as “green” biofactories that generate molecules of our ...
DANEI, MARCO
core  

Expression Pattern and Functional Analysis of MebHLH149 Gene in Response to Cassava Bacterial Blight

Plants
The significant reduction in cassava (Manihot esculenta Crantz) yields attributed to cassava bacterial blight (CBB) constitutes an urgent matter demanding prompt attention.
Min Cui, Feifei An, Songbi Chen, Xindao Qin   +3 more
doaj   +1 more source

Overexpression of PIF4 affects plant morphology and accelerates reproductive phase transitions in soybean

Food and Energy Security, 2021
Phytochrome‐interacting factor 4 acts as a signalling hub for integrating multiple environmental cues like light and temperature. While the function of PIF4 in the model plant Arabidopsis has been studied, there is limited knowledge regarding the role of
Hina Arya, Mohan B. Singh, Prem L. Bhalla   +2 more
doaj   +1 more source

Verification of circMORC3 overexpression plasmid.

, 2023
(A) Sanger sequencing validation of circMORC3, Flag-circMORC3, and Flag-circMORC3-ATG-mut overexpression plasmid capable of producing circular circMORC3.
Weiwei Zheng (140828), Linchao Wang (17706020), Tianjun Xu (138445), Yanhong Song (4516555), Xing Lv (277606)   +4 more
core   +1 more source

NUCKS overexpression in breast cancer [PDF]

Cancer Cell International, 2009
Abstract Background NUCKS (Nuclear, Casein Kinase and Cyclin-dependent Kinase Substrate) is a nuclear, DNA-binding and highly phosphorylated protein. A number of reports show that NUCKS is highly expressed on the level of mRNA in several human cancers, including breast cancer.
Drosos, Yiannis, Kouloukoussa, Mirsini, Østvold, Anne C, Grundt, Kirsten, Goutas, Nikos, Vlachodimitropoulos, Dimitrios, Havaki, Sophia, Kollia, Panagoula, Kittas, Christos, Marinos, Evangelos, Aleporou-Marinou, Vassiliki   +10 more
openaire   +6 more sources