Results 41 to 50 of about 1,507,610 (341)

Expression Profiling of Ribosomal Protein Gene Family in Dehydration Stress Responses and Characterization of Transgenic Rice Plants Overexpressing RPL23A for Water-Use Efficiency and Tolerance to Drought and Salt Stresses

open access: yesFrontiers in Chemistry, 2017
Our previous findings on the screening of a large-pool of activation tagged rice plants grown under limited water conditions revealed the activation of Ribosomal Protein Large (RPL) subunit genes, RPL6 and RPL23A in two mutants that exhibited high water ...
Mazahar Moin   +4 more
doaj   +1 more source

Overexpression of PtoCYCD3

open access: yesInternational Journal of Molecular Sciences, 2021
3.
Guan, Chaonan   +6 more
openaire   +1 more source

Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration [PDF]

open access: yes, 2018
Mutations in Cu/Zn superoxide dismutase 1 (SOD1) lead to Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease that disproportionately affects glutamatergic and cholinergic motor neurons.
Baskoylu, Saba N   +10 more
core   +3 more sources

Mitofusin 2 inhibits high glucose-induced apoptosis of human lens epithelial cells via modulating mitochondrial function and autophagy

open access: yesFolia Histochemica et Cytobiologica
INTRODUCTION: Diabetic cataract (DC) is a common ocular complication of diabetes. Mitofusin 2 (MFN2), a mitochondrial fusion protein, is involved in the pathogenesis of cataract and diabetic complications. However, its role and molecular mechanisms in DC
Yuan-Yi Guo   +4 more
doaj   +1 more source

Centenarians Overexpress Pluripotency-Related Genes

open access: yesThe Journals of Gerontology: Series A, 2018
Abstract Human mesenchymal cells can become pluripotent by the addition of Yamanaka factors OCT3/4, SOX2, c-MYC, KLF4. We have recently reported that centenarians overexpress BCL-xL, which has been shown to improve pluripotency; thus, we aimed to determine the expression of pluripotency-related genes in centenarians.
Inglés de la Torre, Marta   +7 more
openaire   +5 more sources

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. [PDF]

open access: yes, 2016
Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity.
Bakirtzi, K   +25 more
core   +1 more source

Cloning and sequence analysis of goat GSK3B gene and its effect on lipogenesis in goat intramuscular adipocytes

open access: yesJournal of Applied Animal Research
The aim of this study was to detect the expression of GSK3B gene in different tissues of goats and the expression level of intramuscular precursor adipocytes at different differentiation periods, and to further reveal the effects of overexpression and ...
Chengsi Gong   +9 more
doaj   +1 more source

Single-Cell Visualization Deep in Brain Structures by Gene Transfer

open access: yesFrontiers in Neural Circuits, 2020
A projection neuron targets multiple regions beyond the functional brain area. In order to map neuronal connectivity in a massive neural network, a means for visualizing the entire morphology of a single neuron is needed.
Sayaka Sugiyama   +3 more
doaj   +1 more source

Amino acid permease RcAAP1 increases the uptake and phloem translocation of an L-valine-phenazine-1-carboxylic acid conjugate

open access: yesFrontiers in Plant Science, 2023
Amino acid conjugates of pesticides can promote the phloem translocation of parent ingredients, allowing for the reduction of usage, and decreased environmental pollution.
Yongxin Xiao   +3 more
doaj   +1 more source

Overexpressing FSTL1 for Heart Repair

open access: yesTrends in Molecular Medicine, 2016
Myocardial infarction (MI), a major cause of death worldwide, further impairs the inherently low regenerative capacity of cardiomyocytes, with barely 1% of cardiomyocytes per year undergoing cell division [1]. While this low division rate increases in response to MI, it does not compensate for the loss of cardiomyocytes; thus, the area of scarred ...
Sanchís-Gomar, Fabián   +2 more
openaire   +3 more sources

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