Results 41 to 50 of about 1,507,610 (341)
Our previous findings on the screening of a large-pool of activation tagged rice plants grown under limited water conditions revealed the activation of Ribosomal Protein Large (RPL) subunit genes, RPL6 and RPL23A in two mutants that exhibited high water ...
Mazahar Moin +4 more
doaj +1 more source
Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration [PDF]
Mutations in Cu/Zn superoxide dismutase 1 (SOD1) lead to Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease that disproportionately affects glutamatergic and cholinergic motor neurons.
Baskoylu, Saba N +10 more
core +3 more sources
INTRODUCTION: Diabetic cataract (DC) is a common ocular complication of diabetes. Mitofusin 2 (MFN2), a mitochondrial fusion protein, is involved in the pathogenesis of cataract and diabetic complications. However, its role and molecular mechanisms in DC
Yuan-Yi Guo +4 more
doaj +1 more source
Centenarians Overexpress Pluripotency-Related Genes
Abstract Human mesenchymal cells can become pluripotent by the addition of Yamanaka factors OCT3/4, SOX2, c-MYC, KLF4. We have recently reported that centenarians overexpress BCL-xL, which has been shown to improve pluripotency; thus, we aimed to determine the expression of pluripotency-related genes in centenarians.
Inglés de la Torre, Marta +7 more
openaire +5 more sources
Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. [PDF]
Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity.
Bakirtzi, K +25 more
core +1 more source
The aim of this study was to detect the expression of GSK3B gene in different tissues of goats and the expression level of intramuscular precursor adipocytes at different differentiation periods, and to further reveal the effects of overexpression and ...
Chengsi Gong +9 more
doaj +1 more source
Single-Cell Visualization Deep in Brain Structures by Gene Transfer
A projection neuron targets multiple regions beyond the functional brain area. In order to map neuronal connectivity in a massive neural network, a means for visualizing the entire morphology of a single neuron is needed.
Sayaka Sugiyama +3 more
doaj +1 more source
Amino acid conjugates of pesticides can promote the phloem translocation of parent ingredients, allowing for the reduction of usage, and decreased environmental pollution.
Yongxin Xiao +3 more
doaj +1 more source
Overexpressing FSTL1 for Heart Repair
Myocardial infarction (MI), a major cause of death worldwide, further impairs the inherently low regenerative capacity of cardiomyocytes, with barely 1% of cardiomyocytes per year undergoing cell division [1]. While this low division rate increases in response to MI, it does not compensate for the loss of cardiomyocytes; thus, the area of scarred ...
Sanchís-Gomar, Fabián +2 more
openaire +3 more sources

