Results 1 to 10 of about 1,507,610 (341)

Overexpression of DGAT2 Regulates the Differentiation of Bovine Preadipocytes

Animals, 2023
Triacylglycerols (TAGs) are a major component of intramuscular fat. Diacylglycerol O-acyltransferase 2(DGAT2) expression determines the rate of TAG synthesis.
Pan-Pan Guo, Xin Jin, Jun-Fang Zhang, Qiang Li, Chang-Guo Yan, Xiang-Zi Li   +5 more
doaj   +1 more source

Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window? [PDF]

, 2016
LARGE is a glycosyltransferase involved in glycosylation of α-dystroglycan (α-DG). Absence of this protein in the LARGEmyd mouse results in α-DG hypoglycosylation, and is associated with central nervous system abnormalities and progressive muscular ...
A Brancaccio, A von Renesse, A Yoshida, AK Marrone, AM Beedle, AS Pawlisz, Atsushi Asakura, B Constantin, C Whitmore, CJ Moore, D Beltran-Valero de Bernabe, D. J. Wells, DE Michele, DJ Lefeber, E. Lacey, EL McDearmon, F Saito, H. Booler, J Liu, J van Reeuwijk, J. C. W. Hildyard, JM Ervasti, JS Satz, K Kobayashi, K Koehler, KG Meilleur, KJ Carss, KM Wright, LT Guo, M Bozzi, M Brockington, M Kanagawa, M Ogawa, M. Hopkinson, MD Henry, MD Henry, MM Goddeeris, MR Ackroyd, MR Ackroyd, MT Garcia-Silva, O Ibraghimov-Beskrovnaya, O Thompson, P Zhang, PJ Holzfeind, PK Grewal, R Barone, R Barresi, R Shaheen, S Sugita, S Vuillaumier-Barrot, S. C. Brown, T Roscioli, T Toda, T Willer, Y Omori   +54 more
core   +12 more sources

Identification of a Novel Metabolic Target for Bioactive Triterpenoids Biosynthesis in Ganoderma lucidum

Frontiers in Microbiology, 2022
Triterpenoids are crucial active ingredients of Ganoderma lucidum (G. lucidum) with various health benefits. Yet the low biosynthesis greatly restricts their industrial applications, novel metabolic engineering strategies are needed to further enhance ...
Juan Xu, Juan Xu, Juan Xu, Yiyi Wang, Yi Zhang, Kehui Xiong, Xiaoyun Yan, Shiyu Ruan, Xueqian Wu, Xueqian Wu, Xueqian Wu   +10 more
doaj   +1 more source

Constitutive Expression of Arabidopsis Senescence Associated Gene 101 in Brachypodium distachyon Enhances Resistance to Puccinia brachypodii and Magnaporthe oryzae

Plants, 2020
Brachypodium distachyon, as an effective model of cereal grains, is susceptible to most destructive cereal pathogens. Senescence associated gene 101 (SAG101) has been studied extensively in Arabidopsis.
Ning Wang, Na Song, Zejun Tang, Xiaojie Wang, Zhensheng Kang, Liangying Dai, Bing Wang   +6 more
doaj   +1 more source

The Effect of FATP1 on Adipocyte Differentiation in Qinchuan Beef Cattle

Animals, 2021
FATP1 plays an important role in the regulation of fatty acid metabolism and lipid accumulation. In this study, we investigated the patterns of FATP1 expression in various tissues obtained from calf and adult Qinchuan cattle, and in differentiating ...
Xuchun Liu, Shijun Li, Liyun Wang, Weiyi Zhang, Yujuan Wang, Linsheng Gui, Linsen Zan, Chunping Zhao   +7 more
doaj   +1 more source

Phylogenetic and expression analyses of HSF gene families in wheat (Triticum aestivum L.) and characterization of TaHSFB4-2B under abiotic stress

Frontiers in Plant Science, 2023
The heat shock transcription factors (HSFs) family is widely present in eukaryotes including plants. Recent studies have indicated that HSF is a multifunctional group of genes involved in plant growth and development, as well as response to abiotic ...
Liu Yun, Yan Zhang, Shi Li, Jingyu Yang, Changyu Wang, Lanjie Zheng, Li Ji, Jiaheng Yang, Linhu Song, Yong Shi, Xu Zheng, Zhiyong Zhang, Jie Gao, Jie Gao   +13 more
doaj   +1 more source

Role of Her-2/neu in Premalignant and Malignant Lesions of Uterine Cervix [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: In light of literature and controversy that exists in various cervical lesions, this prospective study was designed to explore the expression of Human Epidermal Growth Factor Receptor-2 (HER-2/neu) in the cervical lesions and its ...
SWASTI BAJPAI, SEEMA AWASTHI, SHYAMOLI DUTTA, ANKITA MITTAL, ASHUTOSH KUMAR, FAIYAZ AHMAD   +5 more
doaj   +1 more source

Role of SaPCR2 in Zn Uptake in the Root Elongation Zone of the Zn/Cd Hyperaccumulator Sedum alfredii

Life, 2022
Zn pollution is a potential toxicant for agriculture and the environment. Sedum alfredii is a Zn/Cd hyperaccumulator found in China and has been proven as a useful resource for the phytoremediation of Zn-contaminated sites.
Jun Ge, Jiayu Lin, Zhiying Wu, Kuan Xu, Jingyu Tao, Haizhong Lin, Shengke Tian, Lingli Lu   +7 more
doaj   +1 more source

Galanin overexpressing transgenic mice [PDF]

Neuropeptides, 2002
Galanin overexpressing transgenic mice (GAL-tg) were generated on two different promoters. Both lines of GAL-tg displayed high levels of galanin in the hippocampus and reduced sensitivity to seizures, as compared to their respective wildtype littermate controls (WT).
Bartfai, Tamas, Hohmann, John G., Steiner, Robert A., Xu, Zhi-Qing D., Xu, Xiao-Jun, Holmberg, Kristina, Blakeman, Karin H., Hokfelt, Tomas, Mufson, Elliott J., Crawley, Jacqueline N., Wiesenfeld-Hallin, Zsuzsanna, Teklemichael, Dawit N.   +11 more
openaire   +2 more sources

Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2 [PDF]

, 2009
Angiotensin-converting enzyme (ACE) 2 is a recently identified homologue of ACE. There is great interest in the therapeutic benefit for ACE2 overexpression in the heart.
Allen, James M., Baker, Andrew H., Chamberlain, Jeffrey S., Craig, Margaret Anne, Dominiczak, Anna F., Gilday, Kirsten, Graham, Delyth, Gregorevic, Paul, Masson, Rachel, McBride, Martin, Napoli, Claudio, Nicklin, Stuart A., Smith, Godfrey   +12 more
core   +1 more source