Results 91 to 100 of about 426,067 (292)

The Warburg effect: a signature of mitochondrial overload.

Trends in Cell Biology, 2023
Yahui Wang, Gary J. Patti
semanticscholar   +1 more source

Fabrication Method of Directional Microstructure for High Energy Density, High Power Battery Cathodes

Advanced Materials Interfaces, EarlyView.
Aqueous directional ice templating (DIT) is developed for making NMC811 cathodes containing vertically aligned pore arrays through electrode thickness. The effects of calendering are studied for the DIT electrodes to find optimal calendering and simultaneously achieve high gravimetric and volumetric energy densities and rate capability for lithium ion ...
Guanting Li, Kaiyi Wang, Lin Shen, Chun Huang   +3 more
wiley   +1 more source

Digital workplace technology intensity: qualitative insights on employee wellbeing impacts of digital workplace job demands

Frontiers in Organizational Psychology
IntroductionDigital workplace technologies are powerful enablers in modern organizations but can also threaten employee wellbeing. Drawing on the Job Demands-Resources (JD-R) model, this study explores digital workplace job demands, including ...
Elizabeth Marsh, Elvira Perez Vallejos, Alexa Spence   +2 more
doaj   +1 more source

A Microfluidic Multiplex Sorter for Strain Development

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves, Sebastien Dumont, Zhiyang Deng, Sarah Alkhaldi, Ziuwin Leung, Michelle Oeser, Steve C. C. Shih   +6 more
wiley   +1 more source

Evidence from neuroimaging to explore brain plasticity in humans during an ultra-endurance burden

BMC Medicine, 2012
Physical activity, likely through induction of neuroplasticity, is a promising intervention to promote brain health. In athletes it is clear that training can and does, by physiological adaptations, extend the frontiers of performance capacity.
Perrey Stéphane, Mandrick Kevin
doaj   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

A Multi-Objective Optimization Approach for Corrective Switching of Transmission Systems in Emergency Scenarios

Energies, 2017
The large capacity transmission of power over long distance and the rapid development of renewable energy increase the probability of unexpected emergencies such as overload and under-voltage.
Xin Xu, Yongji Cao, Hengxu Zhang, Shiying Ma, Yunting Song, Dezhi Chen   +5 more
doaj   +1 more source

A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload*

Journal of Biological Chemistry, 2001
Considering that the development of hepatic lesions related to iron overload diseases might be a result of abnormally expressed hepatic genes, we searched for new genes up-regulated under the condition of iron excess.
C. Pigeon, G. Ilyin, Brice Courselaud, P. Leroyer, B. Turlin, P. Brissot, O. Loréal   +6 more
semanticscholar   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source