Results 61 to 70 of about 426,067 (292)

The myosin activator omecamtiv mecarbil improves wall stress in a rat model of chronic aortic regurgitation

open access: yesPhysiological Reports, 2021
In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction.
Bachar El Oumeiri   +8 more
doaj   +1 more source

Iron overload in endometriosis peritoneal fluid induces early embryo ferroptosis mediated by HMOX1

open access: yesCell Death Discovery, 2021
Endometriosis is one of the most common disorders that causes infertility in women. Iron is overloaded in endometriosis peritoneal fluid (PF), with harmful effects on early embryo development.
Shishi Li   +11 more
semanticscholar   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

open access: yesAdvanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes   +4 more
wiley   +1 more source

Role Overload and Work Performance: The Role of Psychological Strain and Leader–Member Exchange

open access: yesFrontiers in Psychology, 2021
The relation between role overload and work performance remains insufficiently understood. Drawing upon conservation of resources theory, we expected role overload to negatively relate to performance through psychological strain and this relation to be ...
Wei‐Gang Tang, C. Vandenberghe
semanticscholar   +1 more source

Effects of Carbon Nanoparticles on Triboelectro‐Induced Surface Defects

open access: yesAdvanced Engineering Materials, EarlyView.
Carbon nanoparticles added to grease modify the electrocontact behavior. The synergy of particle concentration and electric current dominates the surface damage of metals in contact. Electrical surface damage caused by current leakage is a critical challenge in high‐performance applications such as electric vehicle (EV) drivetrains and wind turbine ...
Mohsen Tajedini   +6 more
wiley   +1 more source

Cruciform specimens used for determination of the influence of T-stress on fatigue crack growth with overloads on aluminum alloy Al 6061 T651

open access: yesFracture and Structural Integrity, 2019
The publication presents a cruciform specimen for the determination of cyclic crack growth data under biaxial loading. The design of the specimen with slotted loading arms allows good decoupling between the two loading directions.
Sebastian Henkel   +4 more
doaj  

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction.

open access: yesEuropean Heart Journal, 2019
AIMS Whether and how iron affects the progression of atherosclerosis remains highly debated. Here, we investigate susceptibility to atherosclerosis in a mouse model (ApoE-/- FPNwt/C326S), which develops the disease in the context of elevated non ...
F. Vinchi   +11 more
semanticscholar   +1 more source

MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance

open access: yesAdvanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley   +1 more source

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