Results 61 to 70 of about 700,154 (288)

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Implementasi Load Balancing Pada Web Server Menggunakan Nginx

open access: yesJurnal Teknologi dan Manajemen Informatika, 2020
Kebutuhan internet mempengaruhi pengunjung website semakin meningkat dan membuat beban traffic meningkat pada server, semakin banyak jumlah traffic ke server bisa menyebabkan web server menjadi down, jika digunakan dengan jumlah berlebih (overload ...
Fahmi Apriliansyah   +2 more
doaj   +1 more source

The myosin activator omecamtiv mecarbil improves wall stress in a rat model of chronic aortic regurgitation

open access: yesPhysiological Reports, 2021
In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction.
Bachar El Oumeiri   +8 more
doaj   +1 more source

Optimal routing on complex networks

open access: yes, 2006
We present a novel heuristic algorithm for routing optimization on complex networks. Previously proposed routing optimization algorithms aim at avoiding or reducing link overload. Our algorithm balances traffic on a network by minimizing the maximum node
B. Fortz   +5 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Representing Spatial Geographical Data via variations of Volume and Tempo in Sound [PDF]

open access: yes, 2007
The majority of spatial data are represented visually which can lead to an overload of information if too many data are represented. This study explores and evaluates the methods of representing spatial data using sound, with the aim of increasing the ...
Bearman, N, Tate, N
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Edge overload breakdown in evolving networks

open access: yes, 2002
We investigate growing networks based on Barabasi and Albert's algorithm for generating scale-free networks, but with edges sensitive to overload breakdown. the load is defined through edge betweenness centrality.
A. Broder   +35 more
core   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth   +8 more
wiley   +1 more source

Cruciform specimens used for determination of the influence of T-stress on fatigue crack growth with overloads on aluminum alloy Al 6061 T651

open access: yesFracture and Structural Integrity, 2019
The publication presents a cruciform specimen for the determination of cyclic crack growth data under biaxial loading. The design of the specimen with slotted loading arms allows good decoupling between the two loading directions.
Sebastian Henkel   +4 more
doaj  

Home - About - Disclaimer - Privacy