Results 51 to 60 of about 11,503,776 (284)

Exact Discrete Stochastic Simulation With Deep‐Learning‐Scale Gradient Optimization

open access: yesAdvanced Science, EarlyView.
A 203,796‐parameter gene regulatory network classifies handwritten digits with 98.4% accuracy using exact stochastic dynamics. The framework decouples forward simulation from backward differentiation, making continuous‐time Markov chain models compatible with deep‐learning optimization.
Jose M. G. Vilar, Leonor Saiz
wiley   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

Numerical simulation of structural collapse of container ship in waves based on two-way coupling of CFD nonlinear FEM

open access: yesZhongguo Jianchuan Yanjiu, 2023
ObjectiveThe structural response and dynamic structural collapse mode of a container ship in waves are studied by fully considering the effects of load nonlinearity and surface nonlinearity.MethodsFirst, a hydrodynamic model of a container ship is ...
Weiqin LIU   +6 more
doaj   +1 more source

Foothills model data for overset grid method

open access: yes, 2020
Foohills model file in numerical example for overset grid method. The data is used for reader who wants to reproduce/verify.
openaire   +2 more sources

A Multimoment Finite-Volume Shallow-Water Model On The Yin-Yang Overset Spherical Grid

open access: yes, 2008
A numerical model for shallow-water equations has been built and tested on the Yin-Yang overset spherical grid. A high-order multimoment finite-volume method is used for the spatial discretization in which two kinds of so-called moments of the physical ...
肖锋   +5 more
core   +1 more source

Sticker Valence Governs Chain Collapse and Liquid‐Liquid Phase Separation in Peptide‐Inspired Associative Polymers

open access: yesAdvanced Science, EarlyView.
Peptide‐inspired associative polymers with arginine‐like guanidinium stickers and lysine‐like ammonium spacers undergo chain collapse and liquid‐liquid phase separation induced by reversible sticker associations. Sticker valence and tunable association strength jointly control the phase behavior, chain conformation, and interfacial cohesion of these ...
Seung‐Hwan Oh   +7 more
wiley   +1 more source

A stabilized finite element dynamic overset method for the Navier-Stokes equations [PDF]

open access: yes, 2016
In terms of mesh resolution requirements, higher-order finite element discretization methods offer a more economic means of obtaining accurate simulations and/or to resolve physics at scales not possible with lower-order schemes. For simulations that may
Liu, Chao
core   +3 more sources

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

open access: yesAdvanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song   +6 more
wiley   +1 more source

Investigation of mixed element hybrid grid-based CFD methods for rotorcraft flow analysis [PDF]

open access: yes, 2010
Accurate first-principles flow prediction is essential to the design and development of rotorcraft, and while current numerical analysis tools can, in theory, model the complete flow field, in practice the accuracy of these tools is limited by various ...
Smith, Marlyn J.   +4 more
core   +2 more sources

CFD prediction of submarine motion during emergency surfacing

open access: yesZhongguo Jianchuan Yanjiu, 2019
[Objectives] Emergency surfacing is an important aspect of submarine vitality which is closely related to submarine safety. In order to master the motion laws of submarine during emergency surfacing performance,[Methods] this paper establishes a ...
LI Rijie, CHEN Qinglong, CHANG Wentian
doaj   +1 more source

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