Results 81 to 90 of about 6,251,767 (305)
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
An overview of New England's economic performance in 2010 [PDF]
In the first calendar year following the Great Recession, signs of an economic recovery began to take shape across New England. An improving labor market picture, growth in income, indications of a stabilizing housing market, and booming exports spurred ...
David Coyne+5 more
core
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
The economic performance of the New England states in 2004: an overview [PDF]
The year 2004 marked the beginning of New England’s economic turnaround. After three consecutive years of job losses — not to mention 86 years of World Series famine — the region emerged victorious.
Brad Hershbein+5 more
core
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Growing... but slowing? : an overview of New England's economic performance in 2006 [PDF]
New England’s economic performance was somewhat mixed during 2006. On one hand, all six states added jobs over the course of the year, and the region’s unemployment rate remained steady. The region as a whole picked up jobs in nearly all major industries.
Erin Langlois+5 more
core
Phytochemistry and pharmacology of the genusEntandrophragmaover the 50 years from 1967 to 2018: a ‘golden’ overview [PDF]
Gervais Mouthé Happi+3 more
openalex +1 more source
Most vaccines are designed as a prophylactic measure, that is, to stimulate the immune response so that on subsequent exposure to the particular infectious agent, the extent of infection in the vaccinated individual is so low that disease does not occur.
openaire +5 more sources
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source