Results 91 to 100 of about 6,564,944 (299)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Fanuel Hanán Díaz, Sombras, censuras y tabús en los libros infantiles
Strenae, 2023 Esther Laso y León
doaj +1 more source
, 2005 An overview of LHCb experiment is given, focusing on detector, trigger and expected physics performances. LHCb is a second generation b physics experiment design to do precise measurements of CP violation in B meson system and to study b hadron rare ...
Terrier, H.
core
, 1985 Analytical and experimental work were combined to develop a stress model to determine the temperature profile which will yield a satisfactory web. A thermal model of the web will be used to determine the thermal configuration which will yield the desired
Mcdonald, R. R.
core +1 more source
Hydrophobic interactions: an overview
, 2002 We present an overview of the recent progress that has been made in understanding the origin of hydrophobic interactions. We discuss the different character of the solvation behavior of apolar solutes at small and large length scales.
Attard P +13 more
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Conjecture about mechanism of butterfly-shape coal and gas outburst in excavation roadway
矿业科学学报, 2017 Referring to roadway butterfly shape rock burst mechanism and nonlinear dynamic system theory, a conjecture about butterfly-shape coal and gas outburst mechanism in excavation roadway has been made, In this conjecture, the mechanical essence of coal and ...
Ma Nianjie +5 more
doaj