Results 81 to 90 of about 2,719,020 (292)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Organic Chemestry An Overview

open access: yes, 1978
xv;ill.;384hal ...
Moore,James A.
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Overview showing circular feature

open access: yes, 1999
Image Type: SEM Image, Scale Bar: 500um, Magnification: 80, Etch: No etching, Coating: Au/Pd, Instrument Location: UNM, Scan: med, Spot Sz ...
Melim, L., Spilde, M., Northup, D.
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Conjecture about mechanism of butterfly-shape coal and gas outburst in excavation roadway

open access: yes矿业科学学报, 2017
Referring to roadway butterfly shape rock burst mechanism and nonlinear dynamic system theory, a conjecture about butterfly-shape coal and gas outburst mechanism in excavation roadway has been made, In this conjecture, the mechanical essence of coal and ...
Ma Nianjie   +5 more
doaj  

Interventions for smoking cessation: An overview of Cochrane reviews

open access: yesTobacco Induced Diseases
Introduction Evidence of different smoking cessation interventions varies and has been assessed in many Cochrane reviews. We conducted an overview of these Cochrane reviews to summarize the effects of current interventions for smoking cessation ...
Chun-li Lu   +16 more
doaj   +1 more source

Overview of punky layer

open access: yes, 2005
Image Type: SEM Image, Scale Bar: 1um, Magnification: 9500, Etch: No etching, Coating: Au, Instrument Location: U.
Jones, Brian   +2 more
core  

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