Results 91 to 100 of about 1,628,215 (304)

Telenursing as an Effective Ally for Improving Patient Outcomes in Diabetes? An Umbrella Review

open access: yesNursing Open
Aim To evaluate telenursing interventions' effectiveness in managing patients with diabetes mellitus. Design Overview of systematic reviews. Review Methods According to the PRISMA statement, we included studies published from 2005 to 2023 that evaluated ...
Marika Lo Monaco   +2 more
doaj   +1 more source

The Role of Trade Secrets in Innovation Policy [PDF]

open access: yes, 2010
[Excerpt] This report provides an overview of the law and policy of trade secrets. It discusses the role of trade secrets in U.S. innovation policy. It then reviews the sources of trade secret law and the substantive rules that they provide.
Thomas, John R
core   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

How Has Hospital Consolidation Affected the Price and Quality of Hospital Care? [PDF]

open access: yes, 2006
Provides an overview of the wave of hospital consolidation in the 1990s and reviews the literature on its effects on the prices, costs, and quality of inpatient care.
Robert Town, Wiliam B. Vogt
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Food safety as a public health issue for developing countries [PDF]

open access: yes
"This brief reviews the incidence and health consequences of biological pathogens in developing countries, as these are the most important food safety risks in those parts of the world, and provides an overview of possible methods of control." from ...
Kaferstein, Fritz K.
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Pragmatic methods for reviewing exceptionally large bodies of evidence: systematic mapping review and overview of systematic reviews using lung cancer survival as an exemplar

open access: yesSystematic Reviews, 2019
Introduction Lung cancer (LC) is the most common cause of cancer death in the world and associated with significant economic burden. We conducted a review of published literature to identify prognostic factors associated with LC survival and determine ...
Ruth Lewis   +11 more
doaj   +1 more source

Updating HMDA [PDF]

open access: yes
Carol Lewis of the Boston Fed provides lenders and others who track HMDA (Home Mortgage Disclosure Act) with an overview of changes to the Regulation that takes effect in 2003.
Carol Lewis
core  

Home - About - Disclaimer - Privacy