Results 71 to 80 of about 270,389 (267)

Overview and Historical Review

, 2017
This book investigates and scrutinizes the lessons learned in the Republic of Korea during a five-decade swath of disasters – from 1948 to 2015 – and results in the disaster response policy change model in the wake of major disasters for resilience building. This book is structured of power-law relation between disaster loss and frequency in Korea from
Kim, Yong-kyun, Sohn, Hong-Gyoo
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Pragmatic methods for reviewing exceptionally large bodies of evidence: systematic mapping review and overview of systematic reviews using lung cancer survival as an exemplar

Systematic Reviews, 2019
Introduction Lung cancer (LC) is the most common cause of cancer death in the world and associated with significant economic burden. We conducted a review of published literature to identify prognostic factors associated with LC survival and determine ...
Ruth Lewis, Maggie Hendry, Nafees Din, Marian A. Stanciu, Sadia Nafees, Annie Hendry, Zhi Hao Teoh, Thomas Lloyd, Rachel Parsonage, Richard D. Neal, Gareth Collier, Dyfed W. Huws   +11 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Telenursing as an Effective Ally for Improving Patient Outcomes in Diabetes? An Umbrella Review

Nursing Open
Aim To evaluate telenursing interventions' effectiveness in managing patients with diabetes mellitus. Design Overview of systematic reviews. Review Methods According to the PRISMA statement, we included studies published from 2005 to 2023 that evaluated ...
Marika Lo Monaco, Arianna Profeta, Salvatore Corrao   +2 more
doaj   +1 more source

Mesenchymal stem cells for the treatment of articular cartilage defects of the knee: an overview of systematic reviews [PDF]

Anais da Academia Brasileira de Ciências
There is no consensus on the ideal type, dose, expansion, and differentiation of MSCs for treating knee cartilage defects. Our goal was to perform an overview of systematic reviews regarding the use of MSCs for the treatment of articular cartilage ...
EDUARDO B. DE SOUSA, RENATA AKEMI M. MATSUI, LEONARDO C. BOLDRINI, LEANDRA S. BAPTISTA, JOSÉ MAURO GRANJEIRO   +4 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Anticoagulation in patients with cancer: an overview of reviews

Polish Archives of Internal Medicine, 2008
Relative benefits and harms of anticoagulants are required for judgments regarding appropriate anticoagulation in patients with cancer.To review the benefits and harms of anticoagulants for prophylactic, therapeutic, and survival improvement indications in patients with cancer.Overview of 6 systematic reviews of anticoagulation in cancer following the ...
Elie A, Akl, Paola, Muti, Holger J, Schünemann   +2 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source