Results 121 to 130 of about 935,224 (290)

Screening for hypertension in adults: protocol for evidence reviews to inform a Canadian Task Force on Preventive Health Care guideline update

Systematic Reviews
Purpose To inform updated recommendations by the Canadian Task Force on Preventive Health Care on screening in a primary care setting for hypertension in adults aged 18 years and older.
Nicole Shaver, Andrew Beck, Alexandria Bennett, Brenda J. Wilson, Chantelle Garritty, Melissa Subnath, Roland Grad, Navindra Persaud, Guylène Thériault, Jennifer Flemming, Brett D. Thombs, John LeBlanc, Janusz Kaczorowski, Peter Liu, Christopher E. Clark, Gregory Traversy, Eva Graham, Janusz Feber, Frans H. H. Leenen, Kamila Premji, Robert Pap, Becky Skidmore, Melissa Brouwers, David Moher, Julian Little   +24 more
doaj   +1 more source

Overview of systematic reviews of therapeutic ranges : methodologies and recommendations for practice [PDF]

, 2017
BACKGROUND: Many medicines are dosed to achieve a particular therapeutic range, and monitored using therapeutic drug monitoring (TDM). The evidence base for a therapeutic range can be evaluated using systematic reviews, to ensure it continues to reflect ...
A Konidari, A Sparshatt, A Sparshatt, AC Moreau, AJ Gelenberg, Andrea Jorgensen, BJ Shea, BP Murphy, Centre For Reviews and Dissemination, D Bishara, Daniel Hawcutt, DM Zuk, ES Shinwell, F Buchthal, GW Rylance, Ian Sinha, IP Sinha, JA Sterne, Jamie Kirkham, JJ Cereghino, JP Prybylski, JPT Higgins, JPT Higgins, L Cooney, Lewis Cooney, LW Doyle, M Bialer, M Boers, M Cucherat, M Turner-Warwick, MT Osterman, O Greeff, P Katrak, PR Williamson, R Antonucci, R Kullar, SR Knight, Su Golder, TW Smith, YK Loke, Yoon K. Loke   +40 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Honey for managing oral mucositis induced by cancer therapies: An overview of systematic reviews

Complementary Therapies in Medicine
Purpose: To synthesize and evaluate the quality of systematic reviews focusing on the use of honey for both the prevention and treatment of oral mucositis induced by cancer therapies.
Huda Anshasi, Bassema Abufarsakh, Ja’far M. Alkhawaldeh, Sura Al Halalmeh   +3 more
doaj   +1 more source

NHMRC draft information paper: evidence on the effectiveness of homeopathy for treating health conditions [PDF]

This report summarises an assessment of homeopathy undertaken by the National Health and Medical Research Council, including an overview of published systematic reviews, evaluation of information provided by interest groups and the public, and ...

core  

Primary and secondary prevention of preterm birth: a review of systematic reviews and ongoing randomized controlled trials [PDF]

, 2019
BACKGROUND: Preterm birth (PTB) is a leading cause of perinatal morbidity and mortality. Interventions aimed at preventing PTB can be classified as primary, secondary, or tertiary prevention.
Armson, Anthony B., Matei, Anca, Saccone, Gabriele, Vogel, Joshua P.   +3 more
core   +1 more source

Ginger for health care: An overview of systematic reviews

Complementary Therapies in Medicine, 2019
To summarize the evidence from systematic reviews (SRs) and meta-analyses that evaluated the efficacy of ginger in treating any conditions and critically assess the quality of these evidence.A systematic search of the literature was conducted from inception until February 28, 2019 using the PubMed, EMBASE, Web of science, Cochrane library, and four ...
Huijuan, Li, Yanan, Liu, Dan, Luo, Yuzhen, Ma, Jie, Zhang, Meixuan, Li, Liang, Yao, Xiue, Shi, Xingrong, Liu, Kehu, Yang   +9 more
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Health outcomes of maternal smoking during pregnancy and postpartum period for the mother and infant: protocol for an umbrella review

Systematic Reviews, 2018
Background Internationally, tobacco smoking is a leading cause of mortality, morbidity and health inequality. In England, despite increasing awareness about importance of public health interventions to reduce smoking, about 10% of pregnant women are ...
Tuba Saygın Avşar, Hugh McLeod, Louise Jackson   +2 more
doaj   +1 more source

Acupressure: An Overview of Systematic Reviews [PDF]

Journal of Pain and Symptom Management, 2010
Edzard, Ernst, Myeong Soo, Lee
openaire   +2 more sources