Results 191 to 200 of about 66,023 (384)

Cognitive Limits and the Beginning of Life [PDF]

open access: yes
The question which moral status the embryo has is of great practical significance because the possibility to justify a governmental prohibition of a set of important therapeutical and scientific measures depends on a special and therefore legal ...
Stefan Huster
core  

IL‐1R2 Expression in Tfr Cells Controls Allergic Anaphylaxis by Regulating IgG Versus IgE Responses

open access: yes
Allergy, EarlyView.
Paul Engeroff   +7 more
wiley   +1 more source

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

open access: yesBrain Pathology, EarlyView.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li   +13 more
wiley   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

A RARE CLINICAL CASE OF HETEROTOPIC PREGNANCY

open access: yesМать и дитя в Кузбассе
The article describes a clinical case of heterotopic pregnancy with detection of the ovum in the uterine cavity after salpingectomy for tubal pregnancy. Heterotopic pregnancy is a rare pathology in obstetrics and gynecology.
Лариса Егоровна Фетищева   +6 more
doaj  

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