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Synthesis and biological evaluation of diclofenac acid derivatives as potential lipoxygenase and α-glucosidase inhibitors. [PDF]

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Perfluoro-1,3,4-oxadiazoles

Journal of Fluorine Chemistry, 1992
Abstract Some new polyfluorinated 1,3,4-oxadiazoles have been obtained via a two-step method. The cycloadditions of the 1,3,4-oxadiazoles have been studied and an analysis of the energies of the frontier orbitals calculated by the MNDO method indicates a LUMO-dependent pathway for cycloaddition.
N.V. Vasiliev   +3 more
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Banana-Shaped 1,2,4-Oxadiazole Analogues of 1,3,4-Oxadiazoles

Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals, 2001
Abstract In the last years bent banana-shaped mesomorphic molecules found an increasingly great interest among theoreticians and experimentalists due to the nature of this type of liquid crystals to exhibit a spontaneous polarization in the absence of any chiral group in the molecules.
S. I. TORGOVA   +3 more
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Bioisosterism: 1,2,4‐Oxadiazole Rings

ChemMedChem, 2023
AbstractAlthough studies in drug discovery have gained momentum in recent years, the conversion of drugs in use today into less toxic derivatives with pharmacologically superior properties is still of great importance in drug research. Bioisosterism facilitates the conversion of drugs into derivatives that present more positive pharmacological and ...
Merve Camci, Nilgün Karali
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1,2,4‐Oxadiazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
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1,2,5-Oxadiazoles

ChemInform, 1996
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Poly‐1,3,4‐oxadiazoles. I. Polyphenylene‐1,3,4‐oxadiazoles

Journal of Polymer Science Part A: General Papers, 1965
AbstractPolyphenylene‐1,3,4‐oxadiazoles have been prepared from benzenedicarboxylic acids or their derivatives and hydrazine by solution polycondensation in fuming sulfuric acid or polyphosphoric acid. These polymers were characterized by good thermal stability, and the molecular weights attained were high enough for the products to exhibit fiber‐or ...
Yoshio Iwakura   +2 more
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Banana-shaped 1,2,4-oxadiazoles

Pramana, 2003
3,5-Disubstituted 1,2,4-oxadiazoles are a new type of liquid crystalline (LC) compounds with asymmetrical five-membered heterocycle as a central unit. They have a bent shape and are very convenient model-compounds for studying the dependence of the LC properties on the molecular design.
S. I. TORGOVA   +3 more
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Oxadiazoles in Medicinal Chemistry

Journal of Medicinal Chemistry, 2012
Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms. Oxadiazoles are frequently occurring motifs in druglike molecules, and they are often used with the intention of being bioisosteric replacements for ester and amide functionalities.
Jonas, Boström   +4 more
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